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ZNF117 zinc finger protein 117 [ Homo sapiens (human) ]

Gene ID: 51351, updated on 1-Jun-2020

Summary

Official Symbol
ZNF117provided by HGNC
Official Full Name
zinc finger protein 117provided by HGNC
Primary source
HGNC:HGNC:12897
See related
Ensembl:ENSG00000152926 MIM:194624
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HPF9; H-plk
Summary
This gene encodes a protein containing multiple C2H2-type zinc finger motifs. Readthrough transcription occurs between this gene and the upstream endogenous retrovirus group 3 member 1 (ERV3-1) locus, and may result in additional transcript variants encoding the zinc finger protein. [provided by RefSeq, Jan 2017]
Expression
Ubiquitous expression in adrenal (RPKM 13.2), fat (RPKM 12.9) and 23 other tissues See more
Orthologs

Genomic context

See ZNF117 in Genome Data Viewer
Location:
7q11.21
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (64971776..64991036, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (64434830..64451414, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375328 Neighboring gene metadherin pseudogene 1 Neighboring gene ERV3-1-ZNF117 readthrough Neighboring gene vomeronasal 1 receptor 43 pseudogene Neighboring gene endogenous retrovirus group 3 member 1, envelope Neighboring gene Sharpr-MPRA regulatory region 12375 Neighboring gene uncharacterized LOC105375330 Neighboring gene RNA, U6 small nuclear 1229, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough ERV3-1-ZNF117

Readthrough gene: ERV3-1-ZNF117, Included gene: ERV3-1

Homology

Clone Names

  • MGC22613

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 117
Names
Krueppel-related zinc finger protein
provirus-linked krueppel
zinc finger protein HPF9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015852.4NP_056936.2  zinc finger protein 117

    See identical proteins and their annotated locations for NP_056936.2

    Status: VALIDATED

    Source sequence(s)
    AC073210
    Consensus CDS
    CCDS43593.1
    UniProtKB/Swiss-Prot
    Q03924
    Related
    ENSP00000282869.5, ENST00000282869.11
    Conserved Domains (2) summary
    COG5048
    Location:163475
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:279299
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    64971776..64991036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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