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NEIL1 nei like DNA glycosylase 1 [ Bos taurus (cattle) ]

Gene ID: 513458, updated on 3-Apr-2024

Summary

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Official Symbol
NEIL1provided by VGNC
Official Full Name
nei like DNA glycosylase 1provided by VGNC
Primary source
VGNC:VGNC:31988
See related
BGD:BT30093; Ensembl:ENSBTAG00000007365
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See NEIL1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (33464942..33474052, complement)

Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene SIN3 transcription regulator family member A Neighboring gene mannosidase alpha class 2C member 1 Neighboring gene microRNA mir-631 Neighboring gene COMM domain containing 4 Neighboring gene stress-induced-phosphoprotein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
endonuclease 8-like 1
Names
nei endonuclease VIII-like 1
NP_001014917.2
XP_010815357.2
XP_010815359.2
XP_010815361.2
XP_015314721.2
XP_015314722.2
XP_059735015.1
XP_059735016.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014917.2 → NP_001014917.2  endonuclease 8-like 1

    Status: VALIDATED

    Source sequence(s)
    DAAA02052491
    UniProtKB/TrEMBL
    F1MC42, F1MGF3
    Related
    ENSBTAP00000043635.5, ENSBTAT00000046326.5
    Conserved Domains (3) summary
    pfam06831
    Location:159 → 197
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain
    pfam09292
    Location:252 → 290
    Neil1-DNA_bind; Endonuclease VIII-like 1, DNA bind
    cl03119
    Location:1 → 127
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    33464942..33474052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010817057.4 → XP_010815359.2  endonuclease 8-like 1 isoform X3

    UniProtKB/TrEMBL
    F1MC42, F1MGF3
    Conserved Domains (4) summary
    pfam09292
    Location:252 → 290
    Neil1-DNA_bind; Endonuclease VIII-like 1, DNA bind
    pfam14963
    Location:306 → 399
    CAML; Calcium signal-modulating cyclophilin ligand
    cl03119
    Location:1 → 127
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:52 → 217
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain

  2. XM_059879032.1 → XP_059735015.1  endonuclease 8-like 1 isoform X3

  3. XM_010817055.4 → XP_010815357.2  endonuclease 8-like 1 isoform X3

    UniProtKB/TrEMBL
    F1MC42, F1MGF3
    Related
    ENSBTAP00000050077.3, ENSBTAT00000052162.3
    Conserved Domains (4) summary
    pfam09292
    Location:252 → 290
    Neil1-DNA_bind; Endonuclease VIII-like 1, DNA bind
    pfam14963
    Location:306 → 399
    CAML; Calcium signal-modulating cyclophilin ligand
    cl03119
    Location:1 → 127
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:52 → 217
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain

  4. XM_059879033.1 → XP_059735016.1  endonuclease 8-like 1 isoform X3

  5. XM_010817059.4 → XP_010815361.2  endonuclease 8-like 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MF47
    Conserved Domains (3) summary
    pfam14963
    Location:295 → 388
    CAML; Calcium signal-modulating cyclophilin ligand
    cl03119
    Location:66 → 192
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:117 → 270
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain

  6. XM_015459236.3 → XP_015314722.2  endonuclease 8-like 1 isoform X2

    UniProtKB/TrEMBL
    F1MC42, F1MGF3
    Conserved Domains (3) summary
    pfam09292
    Location:317 → 355
    Neil1-DNA_bind; Endonuclease VIII-like 1, DNA bind
    cl03119
    Location:66 → 192
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:117 → 282
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain

  7. XM_015459235.3 → XP_015314721.2  endonuclease 8-like 1 isoform X1

    UniProtKB/TrEMBL
    F1MC42, F1MGF3
    Conserved Domains (3) summary
    pfam09292
    Location:317 → 355
    Neil1-DNA_bind; Endonuclease VIII-like 1, DNA bind
    cl03119
    Location:66 → 192
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:117 → 282
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain
Nucleotide Protein Strain
Heading Accession and Version

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