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NGRN neugrin, neurite outgrowth associated [ Homo sapiens (human) ]

Gene ID: 51335, updated on 13-Mar-2020

Summary

Official Symbol
NGRNprovided by HGNC
Official Full Name
neugrin, neurite outgrowth associatedprovided by HGNC
Primary source
HGNC:HGNC:18077
See related
Ensembl:ENSG00000182768 MIM:616718
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DSC92
Expression
Ubiquitous expression in brain (RPKM 111.2), prostate (RPKM 60.9) and 25 other tissues See more
Orthologs

Genomic context

See NGRN in Genome Data Viewer
Location:
15q26.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (90265663..90272211)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (90808895..90815443)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene calcium and integrin binding 1 Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene tubulin tyrosine ligase like 13, pseudogene Neighboring gene nucleolar protein interacting with the FHA domain of MKI67 pseudogene 5 Neighboring gene RNA, 7SL, cytoplasmic 736, pseudogene Neighboring gene GOLGA2 pseudogene 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40995

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
rRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
neuron differentiation NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
intercellular bridge IDA
Inferred from Direct Assay
more info
 
mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
mitotic spindle IDA
Inferred from Direct Assay
more info
 
nuclear body IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
neugrin
Names
mesenchymal stem cell protein DSC92
neurite outgrowth associated protein
spinal cord-derived protein FI58G

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033088.3NP_001028260.2  neugrin precursor

    See identical proteins and their annotated locations for NP_001028260.2

    Status: VALIDATED

    Source sequence(s)
    AC091167
    Consensus CDS
    CCDS32329.1
    UniProtKB/Swiss-Prot
    Q9NPE2
    Related
    ENSP00000368389.3, ENST00000379095.4
    Conserved Domains (1) summary
    pfam06413
    Location:73291
    Neugrin; Neugrin

RNA

  1. NR_028052.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AB029315, AI865397, AL834503, BC007222

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    90265663..90272211
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_009454.3: Suppressed sequence

    Description
    NG_009454.3: This RefSeq was removed because the gene was discontinued.
  2. NM_016645.2: Suppressed sequence

    Description
    NM_016645.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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