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ARL17A ADP ribosylation factor like GTPase 17A [ Homo sapiens (human) ]

Gene ID: 51326, updated on 1-Jun-2020

Summary

Official Symbol
ARL17Aprovided by HGNC
Official Full Name
ADP ribosylation factor like GTPase 17Aprovided by HGNC
Primary source
HGNC:HGNC:24096
See related
Ensembl:ENSG00000185829
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARF1P2; ARL17P1
Expression
Ubiquitous expression in lymph node (RPKM 3.4), appendix (RPKM 3.4) and 25 other tissues See more
Orthologs

Genomic context

See ARL17A in Genome Data Viewer
Location:
17q21.31
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (46500213..46579780, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (44577184..44657155, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor like GTPase 17B Neighboring gene Sharpr-MPRA regulatory region 7330 Neighboring gene N-ethylmaleimide-sensitive factor pseudogene 1 Neighboring gene leucine rich repeat containing 37 member A2 Neighboring gene RDM1 pseudogene 2 Neighboring gene RNA, 7SL, cytoplasmic 199, pseudogene Neighboring gene family with sequence similarity 215 member B Neighboring gene N-ethylmaleimide sensitive factor, vesicle fusing ATPase Neighboring gene vesicle-associated membrane protein 5-like Neighboring gene ribosomal protein S7 pseudogene 11

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
ADP-ribosylation factor-like 17-like
Names
ADP-ribosylation factor 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113738.2NP_001107210.1  ADP-ribosylation factor-like 17-like isoform a

    See identical proteins and their annotated locations for NP_001107210.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AB209344, AC138645
    Consensus CDS
    CCDS45718.1
    UniProtKB/Swiss-Prot
    Q8IVW1
    UniProtKB/TrEMBL
    A8K0M5
    Related
    ENSP00000337478.5, ENST00000336125.5
    Conserved Domains (3) summary
    COG1100
    Location:1388
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam15840
    Location:115176
    ARL17; ADP-ribosylation factor-like protein 17
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001288811.1NP_001275740.1  ADP-ribosylation factor-like 17-like isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes an alternate 3' exon structure, compared to variant 1. It encodes isoform c, which is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AC138645, BX102203, DA761795, DA979569, DB065209, HY151357
    Consensus CDS
    CCDS74087.1
    UniProtKB/TrEMBL
    A0A087WVX3
    Related
    ENSP00000331563.5, ENST00000329240.10
    Conserved Domains (3) summary
    COG1100
    Location:1387
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam13900
    Location:93118
    GVQW; Putative domain of unknown function
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. NM_001288812.1NP_001275741.1  ADP-ribosylation factor-like 17-like isoform b

    See identical proteins and their annotated locations for NP_001275741.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) includes an alternate 3' exon structure, compared to variant 1. It encodes isoform b, which is shorter and has a distinct C-terminus, compared to isoform a. Both variants 2 and 4 encode the same isoform (b).
    Source sequence(s)
    CA449330, DB027627, DB065209
    Consensus CDS
    CCDS45717.1
    UniProtKB/Swiss-Prot
    Q8IVW1
    Conserved Domains (1) summary
    cl21455
    Location:188
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. NM_001288813.1NP_001275742.1  ADP-ribosylation factor-like 17-like isoform d

    See identical proteins and their annotated locations for NP_001275742.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) contains an alternate 3' terminal exon, compared to variant 1. It encodes isoform d, which is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AC138645, BX102203, DB065209, DB241677
    Consensus CDS
    CCDS74086.1
    UniProtKB/TrEMBL
    A0A087WY76
    Related
    ENSP00000481578.1, ENST00000622488.6
    Conserved Domains (1) summary
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. NM_001330244.1NP_001317173.1  ADP-ribosylation factor-like 17-like isoform e

    Status: VALIDATED

    Source sequence(s)
    AA911712, AC138645
    Consensus CDS
    CCDS82146.1
    UniProtKB/TrEMBL
    I3L1V5
    Related
    ENSP00000459759.1, ENST00000573185.5
    Conserved Domains (2) summary
    COG1100
    Location:1385
    Gem1; GTPase SAR1 family domain [General function prediction only]
    cl21455
    Location:186
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  6. NM_016632.2NP_057716.2  ADP-ribosylation factor-like 17-like isoform b

    See identical proteins and their annotated locations for NP_057716.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate 3' exon structure, compared to variant 1. It encodes isoform b, which is shorter and has a distinct C-terminus, compared to isoform a. Both variants 2 and 4 encode the same isoform (b).
    Source sequence(s)
    AB209344, AC138645, AF208864
    Consensus CDS
    CCDS45717.1
    UniProtKB/Swiss-Prot
    Q8IVW1
    Related
    ENSP00000416535.2, ENST00000445552.6
    Conserved Domains (1) summary
    cl21455
    Location:188
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    46500213..46579780 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005257439.5XP_005257496.1  ADP-ribosylation factor-like 17-like isoform X4

    See identical proteins and their annotated locations for XP_005257496.1

    UniProtKB/Swiss-Prot
    Q8IVW1
    Conserved Domains (1) summary
    cl21455
    Location:188
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_011524875.3XP_011523177.1  ADP-ribosylation factor-like 17-like isoform X1

    UniProtKB/Swiss-Prot
    Q8IVW1
    Conserved Domains (3) summary
    COG1100
    Location:1388
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam15840
    Location:115175
    ARL17; ADP-ribosylation factor-like protein 17
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_011524876.3XP_011523178.1  ADP-ribosylation factor-like 17-like isoform X2

    See identical proteins and their annotated locations for XP_011523178.1

    Conserved Domains (3) summary
    COG1100
    Location:1388
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam15840
    Location:115176
    ARL17; ADP-ribosylation factor-like protein 17
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_017024729.2XP_016880218.1  ADP-ribosylation factor-like 17-like isoform X2

    Conserved Domains (3) summary
    COG1100
    Location:1388
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam15840
    Location:115176
    ARL17; ADP-ribosylation factor-like protein 17
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. XM_011524877.3XP_011523179.1  ADP-ribosylation factor-like 17-like isoform X3

    See identical proteins and their annotated locations for XP_011523179.1

    UniProtKB/TrEMBL
    I3L3L1
    Conserved Domains (2) summary
    pfam15840
    Location:115176
    ARL17; ADP-ribosylation factor-like protein 17
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_934479.2 RNA Sequence

  2. XR_934476.3 RNA Sequence

  3. XR_934475.3 RNA Sequence

  4. XR_934478.3 RNA Sequence

  5. XR_934477.3 RNA Sequence

  6. XR_934480.3 RNA Sequence

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_187663.1 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    1028373..1099388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003653.1: Suppressed sequence

    Description
    NR_003653.1: This RefSeq was permanently suppressed because it is now thought that this gene expresses a protein.
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