Format

Send to:

Choose Destination

ARMCX1 armadillo repeat containing X-linked 1 [ Homo sapiens (human) ]

Gene ID: 51309, updated on 5-Aug-2018

Summary

Official Symbol
ARMCX1provided by HGNC
Official Full Name
armadillo repeat containing X-linked 1provided by HGNC
Primary source
HGNC:HGNC:18073
See related
Ensembl:ENSG00000126947 MIM:300362; Vega:OTTHUMG00000022033
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ALEX1; GASP7
Summary
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in ovary (RPKM 26.3), adrenal (RPKM 20.2) and 24 other tissues See more
Orthologs

Genomic context

See ARMCX1 in Genome Data Viewer
Location:
Xq22.1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) X NC_000023.11 (101550531..101554700)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (100805466..100809683)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene RPL36A-HNRNPH2 readthrough Neighboring gene heterogeneous nuclear ribonucleoprotein H2 Neighboring gene armadillo repeat containing X-linked 4 Neighboring gene protein kinase C iota pseudogene Neighboring gene armadillo repeat containing X-linked 7, pseudogene Neighboring gene armadillo repeat containing X-linked 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ARMCX4

Homology

Clone Names

  • DKFZp686P06199

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
armadillo repeat-containing X-linked protein 1
Names
ARM protein lost in epithelial cancers on chromosome X 1
arm protein lost in epithelial cancers, X chromosome, 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_015846.1 RefSeqGene

    Range
    5001..9170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_016608.1NP_057692.1  armadillo repeat-containing X-linked protein 1

    See identical proteins and their annotated locations for NP_057692.1

    Status: REVIEWED

    Source sequence(s)
    AB039670
    Consensus CDS
    CCDS14487.1
    UniProtKB/Swiss-Prot
    Q9P291
    UniProtKB/TrEMBL
    A0A024RCI6
    Related
    ENSP00000361917.3, OTTHUMP00000023686, ENST00000372829.7, OTTHUMT00000057561
    Conserved Domains (1) summary
    pfam04826
    Location:196439
    Arm_2; Armadillo-like

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p12 Primary Assembly

    Range
    101550531..101554700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center