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NELFB negative elongation factor complex member B [ Bos taurus (domestic cattle) ]

Gene ID: 512799, updated on 5-Sep-2025
Official Symbol
NELFBprovided by VGNC
Official Full Name
negative elongation factor complex member Bprovided by VGNC
Primary source
VGNC:VGNC:54461
See related
BGD:BT18946; EnsemblRapid:ENSBTAG00070011975
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
COBRA1
Orthologs
human mouse all
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See NELFB in Genome Data Viewer
Location:
chromosome: 11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (106264508..106274378)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene tubulin beta 4B class IVb Neighboring gene family with sequence similarity 166 member A Neighboring gene sperm-tail PG-rich repeat containing 3 Neighboring gene torsin family 4 member A Neighboring gene frizzled-3-like

Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NELF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
negative elongation factor B
Names
cofactor of BRCA1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001435974.1 → NP_001422903.1  negative elongation factor B

    Status: VALIDATED

    Source sequence(s)
    NKLS02000011
    UniProtKB/TrEMBL
    G5E5S2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    106264508..106274378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024999770.2 → XP_024855538.1  negative elongation factor B

    UniProtKB/TrEMBL
    G5E5S2
    Related
    ENSBTAP00070016081.1, ENSBTAT00070026988.1
    Conserved Domains (1) summary
    pfam06209
    Location:307 → 778
    COBRA1; Cofactor of BRCA1 (COBRA1)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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