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ZNF571 zinc finger protein 571 [ Homo sapiens (human) ]

Gene ID: 51276, updated on 5-Aug-2022

Summary

Official Symbol
ZNF571provided by HGNC
Official Full Name
zinc finger protein 571provided by HGNC
Primary source
HGNC:HGNC:25000
See related
Ensembl:ENSG00000180479 AllianceGenome:HGNC:25000
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSPC059
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal (RPKM 2.7), testis (RPKM 2.3) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF571 in Genome Data Viewer
Location:
19q13.12
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (37564260..37594792, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (40366017..40396556, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (38055162..38085693, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZNF793 antisense RNA 1 (head to head) Neighboring gene zinc finger protein 793 Neighboring gene uncharacterized LOC124904708 Neighboring gene ZNF571 antisense RNA 1 Neighboring gene zinc finger protein 540 Neighboring gene MT-ND4 pseudogene 41 Neighboring gene MT-ND5 pseudogene 45 Neighboring gene MT-CO1 pseudogene 41 Neighboring gene ZFP30 zinc finger protein Neighboring gene zinc finger protein 781

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16374, MGC138690

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290314.2NP_001277243.1  zinc finger protein 571

    See identical proteins and their annotated locations for NP_001277243.1

    Status: VALIDATED

    Source sequence(s)
    AK291413, BC040591, BP312315
    Consensus CDS
    CCDS12505.1
    UniProtKB/Swiss-Prot
    Q7Z3V5, Q9NZX7
    UniProtKB/TrEMBL
    A0A024R0L0, A8K5U8
    Related
    ENSP00000351594.3, ENST00000358744.3
    Conserved Domains (3) summary
    COG5048
    Location:193599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:337357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:546
    KRAB; KRAB box
  2. NM_001321272.2NP_001308201.1  zinc finger protein 571

    Status: VALIDATED

    Source sequence(s)
    AC022148, BC040591
    Consensus CDS
    CCDS12505.1
    UniProtKB/Swiss-Prot
    Q7Z3V5, Q9NZX7
    UniProtKB/TrEMBL
    A0A024R0L0
    Related
    ENSP00000467572.1, ENST00000593133.5
    Conserved Domains (3) summary
    COG5048
    Location:193599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:337357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:546
    KRAB; KRAB box
  3. NM_016536.5NP_057620.3  zinc finger protein 571

    See identical proteins and their annotated locations for NP_057620.3

    Status: VALIDATED

    Source sequence(s)
    AF161544, BC040591, BP312315
    Consensus CDS
    CCDS12505.1
    UniProtKB/Swiss-Prot
    Q7Z3V5, Q9NZX7
    UniProtKB/TrEMBL
    A0A024R0L0
    Related
    ENSP00000392638.1, ENST00000451802.7
    Conserved Domains (3) summary
    COG5048
    Location:193599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:337357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:546
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    37564260..37594792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026858.2XP_016882347.1  zinc finger protein 571 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    40366017..40396556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)