CYC1 cytochrome c1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CYC1provided by VGNC
Official Full Name: cytochrome c1provided by VGNC
Primary source: VGNC:VGNC:50266
See related: BGD:BT25214; EnsemblRapid:ENSBTAG00070010864
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	14	NC_037341.1 (738121..740518, complement)

Chromosome 14 - NC_037341.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Holocytochrome c can interact with tRNA but not apocytochrome c that lacks the heme domain.
Title: Perturbation of apoptosis upon binding of tRNA to the heme domain of cytochrome c.
cytochrome c has a role in elimination of reactive oxygen species and hydrogen peroxide from mitochondria, and thus in apoptosis
Title: Effect of cytochrome c on the generation and elimination of O2*- and H2O2 in mitochondria.
An analysis of eight structures of mitochondrial bc(1) with bound quinol oxidation (Q(o)) site inhibitors revealed that the presence of inhibitors causes a bidirectional repositioning of the cd1 helix in the cytochrome b subunit.
Title: Surface-modulated motion switch: capture and release of iron-sulfur protein in the cytochrome bc1 complex.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

CYC1 (e-PCR), detects polymorphism
- UniSTS:278264

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables electron transfer activity	IEA Inferred from Electronic Annotation more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytochrome c1, heme protein, mitochondrial

Names: complex III subunit 4; complex III subunit IV; cytochrome b-c1 complex subunit 4; cytochrome c-1; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit

NP_001033179.1

EC 7.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001038090.2 → NP_001033179.1 cytochrome c1, heme protein, mitochondrial

Status: PROVISIONAL

Source sequence(s)

BC109917

UniProtKB/Swiss-Prot

P00125, Q2TBM2

Related

ENSBTAP00070014566.1, ENSBTAT00070024442.1

Conserved Domains (1) summary

pfam02167
Location:96 → 312

Cytochrom_C1; Cytochrome C1 family