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MTRES1 mitochondrial transcription rescue factor 1 [ Homo sapiens (human) ]

Gene ID: 51250, updated on 21-Dec-2019

Summary

Official Symbol
MTRES1provided by HGNC
Official Full Name
mitochondrial transcription rescue factor 1provided by HGNC
Primary source
HGNC:HGNC:17971
See related
Ensembl:ENSG00000130349 MIM:618583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRED31; HSPC230; C6orf203
Expression
Ubiquitous expression in adrenal (RPKM 9.2), kidney (RPKM 6.8) and 25 other tissues See more
Orthologs

Genomic context

See MTRES1 in Genome Data Viewer
Location:
6q21
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (107028199..107051586)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (107349407..107372546)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 6A pseudogene Neighboring gene CD24 molecule Neighboring gene BEN domain containing 3 Neighboring gene RNA, U6 small nuclear 1299, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ34245

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of mitochondrial transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion HDA PubMed 

General protein information

Preferred Names
mitochondrial transcription rescue factor 1
Names
uncharacterized protein C6orf203

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142468.3NP_001135940.1  mitochondrial transcription rescue factor 1 isoform a

    See identical proteins and their annotated locations for NP_001135940.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 3. Variants 1 and 2 encode the same isoform (a), which has a shorter N-terminus compared to isoform b.
    Source sequence(s)
    AI693246, AK091564, AL355586, CD673918, DA167160, DB499205
    Consensus CDS
    CCDS5058.1
    UniProtKB/Swiss-Prot
    Q9P0P8
    Related
    ENSP00000384867.2, ENST00000405204.6
    Conserved Domains (1) summary
    cl27738
    Location:141227
    YlmH; RNA-binding protein YlmH, contains S4-like domain [General function prediction only]
  2. NM_001142470.3NP_001135942.1  mitochondrial transcription rescue factor 1 isoform b

    See identical proteins and their annotated locations for NP_001135942.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (b).
    Source sequence(s)
    AF151064, AI693246, AK091564, AL355586, BX333652, CD673918, DA167160, DB499205
    Consensus CDS
    CCDS78167.1
    UniProtKB/Swiss-Prot
    Q9P0P8
    UniProtKB/TrEMBL
    A0A0D9SEI0
    Related
    ENSP00000485698.1, ENST00000625458.1
    Conserved Domains (1) summary
    TIGR03069
    Location:146232
    PS_II_S4; photosystem II S4 domain protein
  3. NM_016487.5NP_057571.1  mitochondrial transcription rescue factor 1 isoform a

    See identical proteins and their annotated locations for NP_057571.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 3. Variants 1 and 2 encode the same isoform (a), which has a shorter N-terminus compared to isoform b.
    Source sequence(s)
    AF151064, AI693246, AL355586, CD673918, DA167160, DB499205
    Consensus CDS
    CCDS5058.1
    UniProtKB/Swiss-Prot
    Q9P0P8
    Related
    ENSP00000310951.5, ENST00000311381.8
    Conserved Domains (1) summary
    cl27738
    Location:141227
    YlmH; RNA-binding protein YlmH, contains S4-like domain [General function prediction only]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    107028199..107051586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011535877.3XP_011534179.1  mitochondrial transcription rescue factor 1 isoform X1

    See identical proteins and their annotated locations for XP_011534179.1

    UniProtKB/TrEMBL
    A0A0D9SEI0
    Conserved Domains (1) summary
    TIGR03069
    Location:146232
    PS_II_S4; photosystem II S4 domain protein
  2. XM_017010920.1XP_016866409.1  mitochondrial transcription rescue factor 1 isoform X2

  3. XM_011535876.3XP_011534178.1  mitochondrial transcription rescue factor 1 isoform X1

    See identical proteins and their annotated locations for XP_011534178.1

    UniProtKB/TrEMBL
    A0A0D9SEI0
    Conserved Domains (1) summary
    TIGR03069
    Location:146232
    PS_II_S4; photosystem II S4 domain protein
  4. XM_017010919.2XP_016866408.1  mitochondrial transcription rescue factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A0D9SEI0
    Conserved Domains (1) summary
    TIGR03069
    Location:146232
    PS_II_S4; photosystem II S4 domain protein
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