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HGH1 HGH1 homolog [ Homo sapiens (human) ]

Gene ID: 51236, updated on 19-Jan-2024

Summary

Official Symbol
HGH1provided by HGNC
Official Full Name
HGH1 homologprovided by HGNC
Primary source
HGNC:HGNC:24161
See related
Ensembl:ENSG00000235173 MIM:620684; AllianceGenome:HGNC:24161
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BRP16; BRP16L; FAM203A; FAM203B; C8orf30A; C8orf30B
Expression
Ubiquitous expression in testis (RPKM 6.8), thyroid (RPKM 5.5) and 25 other tissues See more
Orthologs
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Genomic context

See HGH1 in Genome Data Viewer
Location:
8q24.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (144137774..144140851)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (145304495..145307572)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (145192677..145195754)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 2030 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145163585-145164115 Neighboring gene MAF1 homolog, negative regulator of RNA polymerase III Neighboring gene WD repeat domain 97 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28090 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19659 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19660 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19661 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19663 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19662 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19664 Neighboring gene testis specific serine kinase 5, pseudogene Neighboring gene maestro heat like repeat family member 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:145220181-145220332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145220890-145221390 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145222845-145223346 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145223347-145223846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145225713-145226214 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145233092-145233905 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145235445-145236162 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:145236968-145237140 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145239293-145239836 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19665

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
retropepsin gag-pol HIV-1 PR is identified to have a physical interaction with family with sequence similarity 203, member A (FAM203A) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ40907

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
protein HGH1 homolog
Names
brain protein 16
brain protein 16-like
family with sequence similarity 203, member A
family with sequence similarity 203, member B
protein FAM203A
protein FAM203B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016458.4NP_057542.2  protein HGH1 homolog

    See identical proteins and their annotated locations for NP_057542.2

    Status: VALIDATED

    Source sequence(s)
    AC104592, AW002157, BC003035, BC015471
    Consensus CDS
    CCDS6417.1
    UniProtKB/Swiss-Prot
    P0CB43, Q9BTY7
    Related
    ENSP00000321320.5, ENST00000347708.5
    Conserved Domains (2) summary
    pfam04063
    Location:155287
    DUF383; Domain of unknown function (DUF383)
    pfam04064
    Location:292344
    DUF384; Domain of unknown function (DUF384)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    144137774..144140851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001745537.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    145304495..145307572
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_008487850.1 RNA Sequence