U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MEF2C myocyte enhancer factor 2C [ Bos taurus (domestic cattle) ]

Gene ID: 512254, updated on 9-Feb-2026
Official Symbol
MEF2Cprovided by VGNC
Official Full Name
myocyte enhancer factor 2Cprovided by VGNC
Primary source
VGNC:VGNC:31373
See related
BGD:BT26127; EnsemblRapid:ENSBTAG00070019042
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MEF2C in Genome Data Viewer
Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (88246676..88425804, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101904350 Neighboring gene uncharacterized LOC100616526 Neighboring gene microRNA mir-9-2 Neighboring gene BOS complex subunit TMEM147-like Neighboring gene uncharacterized LOC112447486

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene. Juszczuk-Kubiak E, et al. Meat Sci, 2014 Dec. PMID 25108515
  2. Nucleotide sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle. Juszczuk-Kubiak E, et al. Mol Biol Rep, 2011 Feb. PMID 20585884, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The myocyte enhancer factor 2 family of MADS is highly expressed in cells of muscle lineage, where they have been proven to be important regulators of gene expression during the development of skeletal, cardiac and smooth muscle.
    Title: Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene.
  2. analysis of sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle
    Title: Nucleotide sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle.
Submit: New GeneRIF Correction

Markers

Homology

Clone Names

  • MGC137710

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
myocyte-specific enhancer factor 2C
Names
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046113.1 → NP_001039578.1  myocyte-specific enhancer factor 2C

    See identical proteins and their annotated locations for NP_001039578.1

    Status: PROVISIONAL

    Source sequence(s)
    BC112715
    UniProtKB/Swiss-Prot
    Q2KIA0
    UniProtKB/TrEMBL
    D2KFG1
    Related
    ENSBTAP00070025832.1, ENSBTAT00070043107.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107 → 153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    88246676..88425804 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059888100.1 → XP_059744083.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MDH8
    Related
    ENSBTAP00070025868.1, ENSBTAT00070043144.1

  2. XM_059888099.1 → XP_059744082.1  myocyte-specific enhancer factor 2C isoform X4

  3. XM_024994136.2 → XP_024849904.1  myocyte-specific enhancer factor 2C isoform X2

    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  4. XM_059888098.1 → XP_059744081.1  myocyte-specific enhancer factor 2C isoform X3

  5. XM_059888097.1 → XP_059744080.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/TrEMBL
    G3MW05

  6. XM_059888102.1 → XP_059744085.1  myocyte-specific enhancer factor 2C isoform X7

  7. XM_059888101.1 → XP_059744084.1  myocyte-specific enhancer factor 2C isoform X6

    Related
    ENSBTAP00070025845.1, ENSBTAT00070043120.1

  8. XM_024994142.2 → XP_024849910.1  myocyte-specific enhancer factor 2C isoform X4

    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  9. XM_024994141.2 → XP_024849909.1  myocyte-specific enhancer factor 2C isoform X3

    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107 → 153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  10. XM_024994137.2 → XP_024849905.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/TrEMBL
    G3MW05
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107 → 153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  11. XM_024994138.2 → XP_024849906.1  myocyte-specific enhancer factor 2C isoform X3

    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107 → 153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  12. XM_024994134.2 → XP_024849902.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/TrEMBL
    G3MW05
    Related
    ENSBTAP00070025853.1, ENSBTAT00070043129.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107 → 153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  13. XM_059888103.1 → XP_059744086.1  myocyte-specific enhancer factor 2C isoform X8

    Related
    ENSBTAP00070025766.1, ENSBTAT00070043039.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2KIA0.1 GenPept UniProtKB/Swiss-Prot:Q2KIA0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.