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MAEA macrophage erythroblast attacher, E3 ubiquitin ligase [ Bos taurus (domestic cattle) ]

Gene ID: 511956, updated on 9-Feb-2026
Official Symbol
MAEAprovided by VGNC
Official Full Name
macrophage erythroblast attacher, E3 ubiquitin ligaseprovided by VGNC
Primary source
VGNC:VGNC:31135
See related
BGD:BT22921; EnsemblRapid:ENSBTAG00070000081
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MAEA in Genome Data Viewer
Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (117125130..117152555, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene NK1 homeobox 1 Neighboring gene UV stimulated scaffold protein A Neighboring gene uncharacterized LOC101904569 Neighboring gene uncharacterized LOC100299277 Neighboring gene C-terminal binding protein 1

Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC128694

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GID complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein transferase MAEA
NP_001029587.1
XP_024848934.1
XP_024848936.1
XP_059743447.1
XP_059743448.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034415.1 → NP_001029587.1  E3 ubiquitin-protein transferase MAEA

    See identical proteins and their annotated locations for NP_001029587.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105218
    UniProtKB/Swiss-Prot
    A7E3P9, Q3MHJ2
    UniProtKB/TrEMBL
    A0AAA9RU03
    Related
    ENSBTAP00070000080.1, ENSBTAT00070000134.1
    Conserved Domains (5) summary
    smart00667
    Location:120 → 153
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:159 → 254
    CTLH; C-terminal to LisH motif
    smart00757
    Location:250 → 342
    CRA; CT11-RanBPM
    pfam10607
    Location:160 → 339
    CLTH; CTLH/CRA C-terminal to LisH motif domain
    pfam13445
    Location:378 → 417
    zf-RING_UBOX; RING-type zinc-finger

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    117125130..117152555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024993166.2 → XP_024848934.1  E3 ubiquitin-protein transferase MAEA isoform X1

    UniProtKB/TrEMBL
    A0AAA9T3N4
    Related
    ENSBTAP00070000081.1, ENSBTAT00070000135.1
    Conserved Domains (3) summary
    smart00667
    Location:120 → 153
    LisH; Lissencephaly type-1-like homology motif
    pfam10607
    Location:160 → 301
    CLTH; CTLH/CRA C-terminal to LisH motif domain
    cd16659
    Location:336 → 383
    RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins

  2. XM_024993168.2 → XP_024848936.1  E3 ubiquitin-protein transferase MAEA isoform X2

    UniProtKB/TrEMBL
    A0AAA9RU03
    Conserved Domains (3) summary
    smart00667
    Location:72 → 105
    LisH; Lissencephaly type-1-like homology motif
    pfam10607
    Location:112 → 291
    CLTH; CTLH/CRA C-terminal to LisH motif domain
    cd16659
    Location:326 → 373
    RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins

  3. XM_059887464.1 → XP_059743447.1  E3 ubiquitin-protein transferase MAEA isoform X2

    UniProtKB/TrEMBL
    A0AAA9RU03

  4. XM_059887465.1 → XP_059743448.1  E3 ubiquitin-protein transferase MAEA isoform X2

    UniProtKB/TrEMBL
    A0AAA9RU03
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3MHJ2.1 GenPept UniProtKB/Swiss-Prot:Q3MHJ2

Gene LinkOut

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