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TCEAL9 transcription elongation factor A like 9 [ Homo sapiens (human) ]

Gene ID: 51186, updated on 1-Jun-2020

Summary

Official Symbol
TCEAL9provided by HGNC
Official Full Name
transcription elongation factor A like 9provided by HGNC
Primary source
HGNC:HGNC:30084
See related
Ensembl:ENSG00000185222
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WBP5; WEX6
Summary
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein. This gene also encodes a domain with similarity to the transcription elongation factor A, SII-related family. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in placenta (RPKM 88.8), ovary (RPKM 84.9) and 23 other tissues See more
Orthologs

Genomic context

See TCEAL9 in Genome Data Viewer
Location:
Xq22.2
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (103356506..103358462)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (102611380..102613397)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene brain expressed X-linked 2 Neighboring gene transcription elongation factor A like 7 Neighboring gene uncharacterized LL0XNC01-250H12.3 Neighboring gene brain expressed X-linked 3 Neighboring gene RAB40A, member RAS oncogene family

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp313K1940

Gene Ontology Provided by GOA

Function Evidence Code Pubs
WW domain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription elongation factor A protein-like 9
Names
TCEA-like protein 9
WBP-5
WW domain binding protein 1
WW domain-binding protein 5
pp21 homolog
transcription elongation factor S-II protein-like 9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006612.2NP_001006613.1  transcription elongation factor A protein-like 9

    See identical proteins and their annotated locations for NP_001006613.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 4 encode the same isoform.
    Source sequence(s)
    BC023544, BG400091
    Consensus CDS
    CCDS14507.1
    UniProtKB/Swiss-Prot
    Q9UHQ7
    Conserved Domains (1) summary
    pfam04538
    Location:2101
    BEX; Brain expressed X-linked like family
  2. NM_001006613.2NP_001006614.1  transcription elongation factor A protein-like 9

    See identical proteins and their annotated locations for NP_001006614.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 4 encode the same isoform.
    Source sequence(s)
    BC023544, BG400091
    Consensus CDS
    CCDS14507.1
    UniProtKB/Swiss-Prot
    Q9UHQ7
    Related
    ENSP00000361740.3, ENST00000372656.5
    Conserved Domains (1) summary
    pfam04538
    Location:2101
    BEX; Brain expressed X-linked like family
  3. NM_001006614.2NP_001006615.1  transcription elongation factor A protein-like 9

    See identical proteins and their annotated locations for NP_001006615.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 through 4 encode the same isoform.
    Source sequence(s)
    BC023544, BG400091
    Consensus CDS
    CCDS14507.1
    UniProtKB/Swiss-Prot
    Q9UHQ7
    Conserved Domains (1) summary
    pfam04538
    Location:2101
    BEX; Brain expressed X-linked like family
  4. NM_016303.3NP_057387.1  transcription elongation factor A protein-like 9

    See identical proteins and their annotated locations for NP_057387.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1 through 4 encode the same isoform.
    Source sequence(s)
    BC023544, BG400091
    Consensus CDS
    CCDS14507.1
    UniProtKB/Swiss-Prot
    Q9UHQ7
    Related
    ENSP00000361745.3, ENST00000372661.6
    Conserved Domains (1) summary
    pfam04538
    Location:2101
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    103356506..103358462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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