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MBTPS1 membrane bound transcription factor peptidase, site 1 [ Bos taurus (domestic cattle) ]

Gene ID: 511682, updated on 5-Sep-2025
Official Symbol
MBTPS1provided by VGNC
Official Full Name
membrane bound transcription factor peptidase, site 1provided by VGNC
Primary source
VGNC:VGNC:31291
See related
EnsemblRapid:ENSBTAG00070028061
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See MBTPS1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (10389623..10434430, complement)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene oxidative stress induced growth inhibitor 1 Neighboring gene N-terminal EF-hand calcium binding protein 2 Neighboring gene solute carrier family 38 member 8 Neighboring gene uncharacterized LOC112442420 Neighboring gene hydroxysteroid dehydrogenase like 1 Neighboring gene dynein axonemal assembly factor 1

Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC139300

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
membrane-bound transcription factor site-1 protease
NP_001020501.2
XP_005218446.1
XP_005218447.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025330.2 → NP_001020501.2  membrane-bound transcription factor site-1 protease precursor

    See identical proteins and their annotated locations for NP_001020501.2

    Status: PROVISIONAL

    Source sequence(s)
    BC123412
    UniProtKB/TrEMBL
    A0AAA9SD25, F1MJR7, Q08E55
    Related
    ENSBTAP00070038348.1, ENSBTAT00070063878.1
    Conserved Domains (3) summary
    cd07479
    Location:203 → 455
    Peptidases_S8_SKI-1_like; Peptidase S8 family domain in SKI-1-like proteins
    pfam00082
    Location:209 → 464
    Peptidase_S8; Subtilase family
    pfam14258
    Location:651 → 724
    DUF4350; Domain of unknown function (DUF4350)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    10389623..10434430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005218390.5 → XP_005218447.1  membrane-bound transcription factor site-1 protease isoform X2

    See identical proteins and their annotated locations for XP_005218447.1

    UniProtKB/TrEMBL
    A0AAA9SD25
    Conserved Domains (3) summary
    cd07479
    Location:202 → 454
    Peptidases_S8_SKI-1_like; Peptidase S8 family domain in SKI-1-like proteins
    pfam00082
    Location:208 → 463
    Peptidase_S8; Subtilase family
    pfam14258
    Location:650 → 723
    DUF4350; Domain of unknown function (DUF4350)

  2. XM_005218389.5 → XP_005218446.1  membrane-bound transcription factor site-1 protease isoform X1

    See identical proteins and their annotated locations for XP_005218446.1

    UniProtKB/TrEMBL
    A0AAA9SD25, F1MJR7, Q08E55
    Conserved Domains (3) summary
    cd07479
    Location:203 → 455
    Peptidases_S8_SKI-1_like; Peptidase S8 family domain in SKI-1-like proteins
    pfam00082
    Location:209 → 464
    Peptidase_S8; Subtilase family
    pfam14258
    Location:651 → 724
    DUF4350; Domain of unknown function (DUF4350)
Nucleotide Protein Strain
Heading Accession and Version

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