Format

Send to:

Choose Destination

ZNF580 zinc finger protein 580 [ Homo sapiens (human) ]

Gene ID: 51157, updated on 11-Jun-2021

Summary

Official Symbol
ZNF580provided by HGNC
Official Full Name
zinc finger protein 580provided by HGNC
Primary source
HGNC:HGNC:29473
See related
Ensembl:ENSG00000213015 MIM:617888
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in fat (RPKM 10.9), prostate (RPKM 9.2) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF580 in Genome Data Viewer
Location:
19q13.42
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (55641002..55643470)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56152368..56154836)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 784 Neighboring gene uncharacterized LOC107983998 Neighboring gene zinc finger protein 581 Neighboring gene coiled-coil domain containing 106 Neighboring gene U2 small nuclear RNA auxiliary factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 580
Names
LDL-induced EC protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163423.2NP_001156895.1  zinc finger protein 580

    See identical proteins and their annotated locations for NP_001156895.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AC008735, AF184939, BM793208
    Consensus CDS
    CCDS12931.1
    UniProtKB/Swiss-Prot
    Q9UK33
    Related
    ENSP00000446126.1, ENST00000545125.1
    Conserved Domains (2) summary
    sd00017
    Location:94114
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:120142
    zf-C2H2; Zinc finger, C2H2 type
  2. NM_016202.2NP_057286.1  zinc finger protein 580

    See identical proteins and their annotated locations for NP_057286.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AF184939, BM700178, BM710177, BQ477323
    Consensus CDS
    CCDS12931.1
    UniProtKB/Swiss-Prot
    Q9UK33
    Related
    ENSP00000443957.1, ENST00000543039.2
    Conserved Domains (2) summary
    sd00017
    Location:94114
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:120142
    zf-C2H2; Zinc finger, C2H2 type
  3. NM_207115.2NP_996998.1  zinc finger protein 580

    See identical proteins and their annotated locations for NP_996998.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AC008735, AF184939, AL359054, BU179609
    Consensus CDS
    CCDS12931.1
    UniProtKB/Swiss-Prot
    Q9UK33
    Related
    ENSP00000320050.4, ENST00000325333.10
    Conserved Domains (2) summary
    sd00017
    Location:94114
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:120142
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    55641002..55643470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center