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JPT1 Jupiter microtubule associated homolog 1 [ Homo sapiens (human) ]

Gene ID: 51155, updated on 24-Nov-2020

Summary

Official Symbol
JPT1provided by HGNC
Official Full Name
Jupiter microtubule associated homolog 1provided by HGNC
Primary source
HGNC:HGNC:14569
See related
Ensembl:ENSG00000189159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HN1; ARM2; HN1A
Expression
Broad expression in testis (RPKM 36.4), colon (RPKM 19.4) and 21 other tissues See more
Orthologs

Genomic context

See JPT1 in Genome Data Viewer
Location:
17q25.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (75135243..75154512, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (73131343..73150775, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 member 5 Neighboring gene armadillo repeat containing 7 Neighboring gene uncharacterized LOC107985034 Neighboring gene 5', 3'-nucleotidase, cytosolic Neighboring gene small ubiquitin like modifier 2 Neighboring gene nucleoporin 85 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane IDA
Inferred from Direct Assay
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
jupiter microtubule associated homolog 1
Names
androgen-regulated protein 2
hematological and neurological expressed 1 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002032.3NP_001002032.1  jupiter microtubule associated homolog 1 isoform 2

    See identical proteins and their annotated locations for NP_001002032.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) encodes the longest isoform (2).
    Source sequence(s)
    AF086910, AY322169
    Consensus CDS
    CCDS32729.1
    UniProtKB/Swiss-Prot
    Q9UK76
    Related
    ENSP00000348316.4, ENST00000356033.8
    Conserved Domains (1) summary
    pfam17054
    Location:158
    JUPITER; Microtubule-Associated protein Jupiter
  2. NM_001002033.3NP_001002033.1  jupiter microtubule associated homolog 1 isoform 3

    See identical proteins and their annotated locations for NP_001002033.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and contains multiple coding region differences, one of which results in a frameshift and an early stop codon, compared to variant 2. Variants 3, 5 and 6 encode the same isoform (3), which is shorter and has distinct N- and C-termini, compared to isoform 2.
    Source sequence(s)
    AF086910, AY322170
    Consensus CDS
    CCDS45772.1
    UniProtKB/Swiss-Prot
    Q9UK76
  3. NM_001288609.1NP_001275538.1  jupiter microtubule associated homolog 1 isoform 3

    See identical proteins and their annotated locations for NP_001275538.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and contains multiple coding region differences, one of which results in a frameshift and an early stop codon, compared to variant 2. Variants 3, 5 and 6 encode the same isoform (3), which is shorter and has distinct N- and C-termini, compared to isoform 2.
    Source sequence(s)
    AF086910, AW675726, BC039343, DB451153
    Consensus CDS
    CCDS45772.1
    UniProtKB/Swiss-Prot
    Q9UK76
    Related
    ENSP00000464266.1, ENST00000476258.5
  4. NM_001288610.1NP_001275539.1  jupiter microtubule associated homolog 1 isoform 3

    See identical proteins and their annotated locations for NP_001275539.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and contains multiple coding region differences, one of which results in a frameshift and an early stop codon, compared to variant 2. Variants 3, 5 and 6 encode the same isoform (3), which is shorter and has distinct N- and C-termini, compared to isoform 2.
    Source sequence(s)
    AF086910, AK308253, AW675726
    Consensus CDS
    CCDS45772.1
    UniProtKB/Swiss-Prot
    Q9UK76
    Related
    ENSP00000462834.1, ENST00000482348.5
  5. NM_001288611.2NP_001275540.1  jupiter microtubule associated homolog 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an alternate exon in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 2. It encodes isoform 4, which is shorter and has a distinct C-terminus, compared to isoform 2.
    Source sequence(s)
    AC022211, AF086910, BG779109
    UniProtKB/Swiss-Prot
    Q9UK76
    Conserved Domains (1) summary
    pfam17054
    Location:158
    JUPITER; Microtubule-Associated protein Jupiter
  6. NM_016185.4NP_057269.1  jupiter microtubule associated homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_057269.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) contains an alternate exon in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 2. It encodes isoform 1, which is shorter and has a distinct C-terminus, compared to isoform 2.
    Source sequence(s)
    AF266846, AW675726
    Consensus CDS
    CCDS45771.1
    UniProtKB/Swiss-Prot
    Q9UK76
    Related
    ENSP00000387059.3, ENST00000409753.8
    Conserved Domains (1) summary
    pfam17054
    Location:158
    JUPITER; Microtubule-Associated protein Jupiter

RNA

  1. NR_109933.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) uses an alternate splice site in an internal exon and contains an alternate internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF086910, DA604735

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    75135243..75154512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450779.1XP_024306547.1  jupiter microtubule associated homolog 1 isoform X1

    Related
    ENSP00000462478.1, ENST00000481647.5
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