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RPL26L1 ribosomal protein L26 like 1 [ Homo sapiens (human) ]

Gene ID: 51121, updated on 11-Jun-2021

Summary

Official Symbol
RPL26L1provided by HGNC
Official Full Name
ribosomal protein L26 like 1provided by HGNC
Primary source
HGNC:HGNC:17050
See related
Ensembl:ENSG00000037241
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RPL26P1
Summary
This gene encodes a protein that shares high sequence similarity with ribosomal protein L26. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Dec 2015]
Expression
Ubiquitous expression in testis (RPKM 13.8), kidney (RPKM 5.9) and 25 other tissues See more
Orthologs
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Genomic context

See RPL26L1 in Genome Data Viewer
Location:
5q35.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (172953677..172969771)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (172385732..172396774)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr5.4451 Neighboring gene endoplasmic reticulum-golgi intermediate compartment 1 Neighboring gene microRNA 10523 Neighboring gene uncharacterized LOC100268168 Neighboring gene Sharpr-MPRA regulatory region 5956 Neighboring gene inorganic pyrophosphatase 1 pseudogene Neighboring gene ATPase H+ transporting V0 subunit e1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ46904

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 

General protein information

Preferred Names
60S ribosomal protein L26-like 1
Names
large ribosomal subunit protein uL24-like 1
ribosomal protein L26 homolog
ribosomal protein L26 pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001317980.2NP_001304909.1  60S ribosomal protein L26-like 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC008429, BC017360, BU193755
    Consensus CDS
    CCDS4382.1
    UniProtKB/Swiss-Prot
    Q9UNX3
    Related
    ENSP00000428223.1, ENST00000521476.5
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
  2. NM_001317981.2NP_001304910.1  60S ribosomal protein L26-like 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    BC017360, BI838595
    Consensus CDS
    CCDS4382.1
    UniProtKB/Swiss-Prot
    Q9UNX3
    Related
    ENSP00000428177.1, ENST00000519974.5
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
  3. NM_001317982.2NP_001304911.1  60S ribosomal protein L26-like 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC008429, BC017360, BQ278240, BU569345
    Consensus CDS
    CCDS4382.1
    UniProtKB/Swiss-Prot
    Q9UNX3
    Related
    ENSP00000430147.1, ENST00000519239.5
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
  4. NM_016093.4NP_057177.1  60S ribosomal protein L26-like 1

    See identical proteins and their annotated locations for NP_057177.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    BC017360, HY015036
    Consensus CDS
    CCDS4382.1
    UniProtKB/Swiss-Prot
    Q9UNX3
    Related
    ENSP00000265100.2, ENST00000265100.6
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    172953677..172969771
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011534565.2XP_011532867.1  60S ribosomal protein L26-like 1 isoform X1

    See identical proteins and their annotated locations for XP_011532867.1

    UniProtKB/Swiss-Prot
    Q9UNX3
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
  2. XM_017009520.1XP_016865009.1  60S ribosomal protein L26-like 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9UNX3
    Related
    ENSP00000430673.1, ENST00000519156.1
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
  3. XM_017009519.2XP_016865008.1  60S ribosomal protein L26-like 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9UNX3
    Conserved Domains (2) summary
    PRK05431
    Location:109145
    PRK05431; seryl-tRNA synthetase; Provisional
    pfam16906
    Location:8122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
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