U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UTP11 UTP11 small subunit processome component [ Homo sapiens (human) ]

Gene ID: 51118, updated on 3-May-2025
Official Symbol
UTP11provided by HGNC
Official Full Name
UTP11 small subunit processome componentprovided by HGNC
Primary source
HGNC:HGNC:24329
See related
Ensembl:ENSG00000183520 MIM:609440; AllianceGenome:HGNC:24329
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI94; CGI-94; UTP11L
Summary
Enables RNA binding activity. Involved in nervous system development; positive regulation of apoptotic process; and ribosomal small subunit biogenesis. Located in cytosol; extracellular space; and nuclear lumen. Part of small-subunit processome. [provided by Alliance of Genome Resources, May 2025]
Expression
Ubiquitous expression in adrenal (RPKM 11.3), esophagus (RPKM 10.1) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table
See UTP11 in Genome Data Viewer
Location:
1p34.3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (38012734..38024820)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (37879913..37892000)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (38478406..38490492)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 8264 Neighboring gene RNA, U6 small nuclear 510, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38463160-38464081 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38465171-38465958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38465959-38466746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38469196-38470004 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 684 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 782 Neighboring gene four and a half LIM domains 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:38491775-38492274 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38492441-38492993 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38492994-38493545 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 783 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 784 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 785 Neighboring gene Sharpr-MPRA regulatory region 3132 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38512768-38513268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38513269-38513769 Neighboring gene MIR3659 host gene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 687 Neighboring gene POU class 3 homeobox 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 786 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 787 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38537009-38537508 Neighboring gene microRNA 3659

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small-subunit processome IDA
Inferred from Direct Assay
more info
PubMed 
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
probable U3 small nucleolar RNA-associated protein 11
Names
U3 snoRNA-associated protein 11
UTP11, small subunit processome component homolog
UTP11-like protein
UTP11-like, U3 small nucleolar ribonucleoprotein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016037.4NP_057121.2  probable U3 small nucleolar RNA-associated protein 11

    See identical proteins and their annotated locations for NP_057121.2

    Status: VALIDATED

    Source sequence(s)
    AF151852, BI493106, BU620078, BU940926, CX163866
    Consensus CDS
    CCDS429.1
    UniProtKB/Swiss-Prot
    A8K785, B4DJC6, D3DPT7, Q5VT93, Q9BS98, Q9NS31, Q9Y3A2
    Related
    ENSP00000362105.4, ENST00000373014.5
    Conserved Domains (1) summary
    pfam03998
    Location:13253
    Utp11; Utp11 protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    38012734..38024820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541555.3XP_011539857.1  probable U3 small nucleolar RNA-associated protein 11 isoform X1

    See identical proteins and their annotated locations for XP_011539857.1

    Conserved Domains (1) summary
    pfam03998
    Location:1184
    Utp11; Utp11 protein

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    37879913..37892000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054336893.1XP_054192868.1  probable U3 small nucleolar RNA-associated protein 11 isoform X1