Format

Send to:

Choose Destination

SIDT2 SID1 transmembrane family member 2 [ Homo sapiens (human) ]

Gene ID: 51092, updated on 18-Aug-2020

Summary

Official Symbol
SIDT2provided by HGNC
Official Full Name
SID1 transmembrane family member 2provided by HGNC
Primary source
HGNC:HGNC:24272
See related
Ensembl:ENSG00000149577 MIM:617551
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI-40
Expression
Ubiquitous expression in stomach (RPKM 22.3), prostate (RPKM 21.9) and 25 other tissues See more
Orthologs

Genomic context

See SIDT2 in Genome Data Viewer
Location:
11q23.3
Exon count:
26
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (117178743..117197442)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (117049626..117068161)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene proprotein convertase subtilisin/kexin type 7 pseudogene Neighboring gene platelet activating factor acetylhydrolase 1b catalytic subunit 2 Neighboring gene uncharacterized LOC100652768 Neighboring gene transgelin Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene ring finger protein 214 Neighboring gene beta-secretase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: TAGLN

Homology

Clone Names

  • FLJ90656, DKFZp686L17253

Gene Ontology Provided by GOA

Function Evidence Code Pubs
AP-1 adaptor complex binding ISS
Inferred from Sequence or Structural Similarity
more info
 
AP-2 adaptor complex binding ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleic acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
RNA catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
RNA transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA transport IDA
Inferred from Direct Assay
more info
PubMed 
cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 
glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
regulation of insulin secretion involved in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 
response to glucose IEA
Inferred from Electronic Annotation
more info
 
type B pancreatic cell development IEA
Inferred from Electronic Annotation
more info
 
type B pancreatic cell proliferation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
SID1 transmembrane family member 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040455.2NP_001035545.1  SID1 transmembrane family member 2 precursor

    See identical proteins and their annotated locations for NP_001035545.1

    Status: VALIDATED

    Source sequence(s)
    AP005018, AY358442
    Consensus CDS
    CCDS31682.1
    UniProtKB/Swiss-Prot
    Q8NBJ9
    Related
    ENSP00000314023.4, ENST00000324225.9
    Conserved Domains (1) summary
    pfam13965
    Location:172832
    SID-1_RNA_chan; dsRNA-gated channel SID-1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    117178743..117197442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_015996.1: Suppressed sequence

    Description
    NM_015996.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Support Center