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LTBP1 latent transforming growth factor beta binding protein 1 [ Bos taurus (domestic cattle) ]

Gene ID: 510559, updated on 5-Sep-2025
Official Symbol
LTBP1provided by VGNC
Official Full Name
latent transforming growth factor beta binding protein 1provided by VGNC
Primary source
VGNC:VGNC:31071
See related
EnsemblRapid:ENSBTAG00070011144
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See LTBP1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (15473629..15930112)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 27 Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene RAS guanyl releasing protein 3 Neighboring gene family with sequence similarity 98 member A

Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Fibrillins and latent TGFbeta binding proteins in bovine ovaries of offspring following high or low protein diets during pregnancy of dams. Prodoehl MJ, et al. Mol Cell Endocrinol, 2009 Aug 13. PMID 19524133
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This is the first study to investigate the expression and localization of fibrillin proteins and latent TGF-beta binding proteins affecting TGFbeta bioavailability in the ovary.
    Title: Fibrillins and latent TGFbeta binding proteins in bovine ovaries of offspring following high or low protein diets during pregnancy of dams.
Submit: New GeneRIF Correction

Markers

Homology

Clone Names

  • MGC166121

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
latent-transforming growth factor beta-binding protein 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103091.1 → NP_001096561.1  latent-transforming growth factor beta-binding protein 1 precursor

    See identical proteins and their annotated locations for NP_001096561.1

    Status: PROVISIONAL

    Source sequence(s)
    BC151354
    UniProtKB/TrEMBL
    A0A3Q1M8C7, A7YY58
    Conserved Domains (4) summary
    smart00179
    Location:821 → 862
    EGF_CA; Calcium-binding EGF-like domain
    pfam00683
    Location:361 → 395
    TB; TB domain
    pfam07645
    Location:534 → 574
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:515 → 537
    cEGF; Complement Clr-like EGF-like

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    15473629..15930112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024998486.2 → XP_024854254.1  latent-transforming growth factor beta-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LF45, F1N444
    Related
    ENSBTAP00070015001.1, ENSBTAT00070025217.1
    Conserved Domains (6) summary
    smart00179
    Location:1191 → 1232
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:987 → 1020
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:678 → 717
    TB; TB domain
    pfam07645
    Location:904 → 944
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:885 → 907
    cEGF; Complement Clr-like EGF-like
    cl26464
    Location:731 → 857
    Atrophin-1; Atrophin-1 family

  2. XM_024998488.2 → XP_024854256.1  latent-transforming growth factor beta-binding protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LF45
    Conserved Domains (6) summary
    smart00179
    Location:1191 → 1232
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:987 → 1020
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:678 → 717
    TB; TB domain
    pfam07645
    Location:904 → 944
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:885 → 907
    cEGF; Complement Clr-like EGF-like
    cl26464
    Location:731 → 857
    Atrophin-1; Atrophin-1 family

  3. XM_024998487.2 → XP_024854255.1  latent-transforming growth factor beta-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LF45
    Conserved Domains (6) summary
    smart00179
    Location:1190 → 1231
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:986 → 1019
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:678 → 717
    TB; TB domain
    pfam07645
    Location:903 → 943
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:884 → 906
    cEGF; Complement Clr-like EGF-like
    cl27169
    Location:740 → 858
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...

  4. XM_024998489.2 → XP_024854257.1  latent-transforming growth factor beta-binding protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1LF45
    Conserved Domains (5) summary
    smart00179
    Location:1138 → 1179
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:934 → 967
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:1293 → 1334
    TB; TB domain
    pfam07645
    Location:851 → 891
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:832 → 854
    cEGF; Complement Clr-like EGF-like

  5. XM_024998492.2 → XP_024854260.1  latent-transforming growth factor beta-binding protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A3Q1LF45, F1MJM5
    Related
    ENSBTAP00070015018.1, ENSBTAT00070025237.1
    Conserved Domains (5) summary
    smart00179
    Location:1138 → 1179
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:934 → 967
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:1251 → 1292
    TB; TB domain
    pfam07645
    Location:851 → 891
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:832 → 854
    cEGF; Complement Clr-like EGF-like

  6. XM_024998490.2 → XP_024854258.1  latent-transforming growth factor beta-binding protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LF45
    Conserved Domains (5) summary
    smart00179
    Location:1137 → 1178
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:933 → 966
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:1292 → 1333
    TB; TB domain
    pfam07645
    Location:850 → 890
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:831 → 853
    cEGF; Complement Clr-like EGF-like

  7. XM_024998491.2 → XP_024854259.1  latent-transforming growth factor beta-binding protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A3Q1LF45
    Related
    ENSBTAP00070015036.1, ENSBTAT00070025261.1
    Conserved Domains (6) summary
    smart00179
    Location:1135 → 1176
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:931 → 964
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:622 → 661
    TB; TB domain
    pfam07645
    Location:848 → 888
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:829 → 851
    cEGF; Complement Clr-like EGF-like
    cl26464
    Location:675 → 801
    Atrophin-1; Atrophin-1 family

  8. XM_059891159.1 → XP_059747142.1  latent-transforming growth factor beta-binding protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A3Q1M8C7

  9. XM_024998493.2 → XP_024854261.1  latent-transforming growth factor beta-binding protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A3Q1M8C7
    Conserved Domains (6) summary
    smart00179
    Location:874 → 915
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:670 → 703
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:361 → 400
    TB; TB domain
    pfam07645
    Location:587 → 627
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:568 → 590
    cEGF; Complement Clr-like EGF-like
    cl26464
    Location:414 → 540
    Atrophin-1; Atrophin-1 family

  10. XM_059891160.1 → XP_059747143.1  latent-transforming growth factor beta-binding protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1M8C7

  11. XM_059891161.1 → XP_059747144.1  latent-transforming growth factor beta-binding protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A3Q1M8C7

  12. XM_024998494.2 → XP_024854262.1  latent-transforming growth factor beta-binding protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A3Q1M8C7
    Conserved Domains (5) summary
    smart00179
    Location:821 → 862
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:617 → 650
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00683
    Location:934 → 975
    TB; TB domain
    pfam07645
    Location:534 → 574
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:515 → 537
    cEGF; Complement Clr-like EGF-like

  13. XM_059891162.1 → XP_059747145.1  latent-transforming growth factor beta-binding protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A3Q1M8C7

  14. XM_059891163.1 → XP_059747146.1  latent-transforming growth factor beta-binding protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A3Q1M8C7
Nucleotide Protein Strain
Heading Accession and Version

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