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GOLT1B golgi transport 1B [ Homo sapiens (human) ]

Gene ID: 51026, updated on 24-Nov-2020

Summary

Official Symbol
GOLT1Bprovided by HGNC
Official Full Name
golgi transport 1Bprovided by HGNC
Primary source
HGNC:HGNC:20175
See related
Ensembl:ENSG00000111711 MIM:615078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GCT2; GOT1; GOT1B; CGI-141; YMR292W
Expression
Ubiquitous expression in placenta (RPKM 8.4), adrenal (RPKM 8.0) and 25 other tissues See more
Orthologs

Genomic context

See GOLT1B in Genome Data Viewer
Location:
12p12.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (21501176..21518408)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (21654699..21671337)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family member 1A2 Neighboring gene islet amyloid polypeptide Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene elongin C pseudogene 31 Neighboring gene RecQ like helicase Neighboring gene spexin hormone Neighboring gene glycogen synthase 2 Neighboring gene lactate dehydrogenase B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of I-kappaB kinase/NF-kappaB signaling HMP PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane HDA PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
vesicle transport protein GOT1B
Names
germ cell tumor 2
hGOT1a
putative NF-kappa-B-activating protein 470

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016072.5NP_057156.1  vesicle transport protein GOT1B

    See identical proteins and their annotated locations for NP_057156.1

    Status: VALIDATED

    Source sequence(s)
    AA910170, AB097020, AC006559, DA579356
    Consensus CDS
    CCDS8689.1
    UniProtKB/Swiss-Prot
    Q9Y3E0
    Related
    ENSP00000229314.4, ENST00000229314.10
    Conserved Domains (1) summary
    cl02130
    Location:4120
    Got1; Got1/Sft2-like family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    21501176..21518408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448999.1XP_024304767.1  vesicle transport protein GOT1B isoform X1

    Conserved Domains (1) summary
    cl02130
    Location:102218
    Got1; Got1/Sft2-like family
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