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TARS threonyl-tRNA synthetase [ Bos taurus (cattle) ]

Gene ID: 510075, updated on 2-Oct-2018

Summary

Official Symbol
TARSprovided by VGNC
Official Full Name
threonyl-tRNA synthetaseprovided by VGNC
Primary source
VGNC:VGNC:35605
See related
BGD:BT16017; Ensembl:ENSBTAG00000014261
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See TARS in Genome Data Viewer
Location:
chromosome: 20
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 20 NC_037347.1 (40309681..40333122, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 20 AC_000177.1 (40349620..40373084, complement)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 12 Neighboring gene relaxin family peptide receptor 3 Neighboring gene transfer RNA threonine (anticodon UGU) Neighboring gene uncharacterized LOC107131571 Neighboring gene natriuretic peptide receptor 3

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC128147

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
threonine-tRNA ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
threonyl-tRNA aminoacylation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
threonine--tRNA ligase, cytoplasmic
Names
thrRS
threonyl-tRNA synthetase, cytoplasmic
NP_001029542.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034370.2NP_001029542.1  threonine--tRNA ligase, cytoplasmic

    See identical proteins and their annotated locations for NP_001029542.1

    Status: PROVISIONAL

    Source sequence(s)
    BC103082
    UniProtKB/Swiss-Prot
    Q3ZBV8
    Related
    ENSBTAP00000018947.3, ENSBTAT00000018947.3
    Conserved Domains (5) summary
    cd01667
    Location:83144
    TGS_ThrRS_N; TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and ...
    PLN02908
    Location:37716
    PLN02908; threonyl-tRNA synthetase
    smart00863
    Location:250297
    tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain
    cd00771
    Location:321618
    ThrRS_core; Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent ...
    cd00860
    Location:618709
    ThrRS_anticodon; ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    40309681..40333122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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