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Pdcd7 programmed cell death 7 [ Mus musculus (house mouse) ]

Gene ID: 50996, updated on 20-Jun-2024

Summary

Official Symbol
Pdcd7provided by MGI
Official Full Name
programmed cell death 7provided by MGI
Primary source
MGI:MGI:1859170
See related
Ensembl:ENSMUSG00000041837 AllianceGenome:MGI:1859170
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ES18
Summary
Involved in response to glucocorticoid. Acts upstream of or within positive regulation of T cell apoptotic process and positive regulation of apoptotic signaling pathway. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex. Is expressed in several structures, including brain ventricular layer; chondrocranium; jaw; submandibular gland primordium; and vibrissa. Orthologous to human PDCD7 (programmed cell death 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 12.0), ovary adult (RPKM 11.7) and 28 other tissues See more
Orthologs
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Genomic context

See Pdcd7 in Genome Data Viewer
Location:
9 C; 9 35.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65253350..65266925)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65346068..65359643)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene 16218 Neighboring gene caseinolytic mitochondrial matrix peptidase chaperone subunit Neighboring gene predicted gene, 19219 Neighboring gene STARR-seq mESC enhancer starr_24452 Neighboring gene ubiquitin-associated protein 1-like Neighboring gene predicted gene, 17875 Neighboring gene kelch repeat and BTB (POZ) domain containing 13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
programmed cell death protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016688.2NP_057897.2  programmed cell death protein 7

    See identical proteins and their annotated locations for NP_057897.2

    Status: VALIDATED

    Source sequence(s)
    AC114645, BE946822, BU518553, DV656988
    Consensus CDS
    CCDS40670.1
    UniProtKB/Swiss-Prot
    Q8R5D9, Q9WTY1
    UniProtKB/TrEMBL
    Q3U2X6
    Related
    ENSMUSP00000035515.3, ENSMUST00000048184.4
    Conserved Domains (1) summary
    pfam16021
    Location:168481
    PDCD7; Programmed cell death protein 7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    65253350..65266925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)