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CSF1R colony stimulating factor 1 receptor [ Bos taurus (domestic cattle) ]

Gene ID: 509418, updated on 5-Sep-2025
Official Symbol
CSF1Rprovided by VGNC
Official Full Name
colony stimulating factor 1 receptorprovided by VGNC
Primary source
VGNC:VGNC:27754
See related
BGD:BT28752; EnsemblRapid:ENSBTAG00070004424
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See CSF1R in Genome Data Viewer
Location:
chromosome: 7
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (61380050..61411558, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 6A Neighboring gene solute carrier family 26 member 2 Neighboring gene HMG-box containing 3 Neighboring gene platelet derived growth factor receptor beta Neighboring gene microRNA mir-1777b Neighboring gene caudal type homeobox 1

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Synteny mapping in the bovine: genes from human chromosome 5. Zhang N, et al. Genomics, 1992 Sep. PMID 1385298
  2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables macrophage colony-stimulating factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in osteoclast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CSF1-CSF1R complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
macrophage colony-stimulating factor 1 receptor
Names
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog
NP_001068871.2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075403.2 → NP_001068871.2  macrophage colony-stimulating factor 1 receptor precursor

    See identical proteins and their annotated locations for NP_001068871.2

    Status: PROVISIONAL

    Source sequence(s)
    BC153265
    UniProtKB/TrEMBL
    A0AAF6DLP5, A7Z067, F1MWJ7
    Related
    ENSBTAP00070005793.1, ENSBTAT00070010073.1
    Conserved Domains (6) summary
    cd00096
    Location:415 → 492
    Ig; Immunoglobulin domain
    smart00410
    Location:209 → 290
    IG_like; Immunoglobulin like
    pfam00047
    Location:207 → 293
    ig; Immunoglobulin domain
    pfam07714
    Location:579 → 908
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:299 → 398
    Ig; Immunoglobulin domain
    cl21453
    Location:540 → 912
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61380050..61411558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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