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Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 [ Mus musculus (house mouse) ]

Gene ID: 50934, updated on 3-Jun-2018
Official Symbol
Slc7a8provided by MGI
Official Full Name
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8provided by MGI
Primary source
MGI:MGI:1355323
See related
Ensembl:ENSMUSG00000022180
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LAT2; AA408822
Expression
Biased expression in kidney adult (RPKM 137.5), duodenum adult (RPKM 56.6) and 13 other tissues See more
Orthologs
See Slc7a8 in Genome Data Viewer
Location:
14; 14 C2
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (54722215..54781886, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55341052..55400723, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29776 Neighboring gene CCAAT/enhancer binding protein (C/EBP), epsilon Neighboring gene ring finger protein 212B Neighboring gene developmental pluripotency-associated protein 5A-like Neighboring gene homeodomain leucine zipper-encoding gene

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
amine transmembrane transporter activity ISA
Inferred from Sequence Alignment
more info
PubMed 
amino acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
neutral amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organic cation transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
toxin transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-amino acid transport IDA
Inferred from Direct Assay
more info
PubMed 
amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
amino acid transport ISA
Inferred from Sequence Alignment
more info
PubMed 
amino acid transport ISO
Inferred from Sequence Orthology
more info
 
neutral amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
large neutral amino acids transporter small subunit 2
Names
L-type amino acid transporter 2
mLAT2
solute carrier family 7 member 8
solute carrier family 8 (cationic amino acid transporter, y+ system), member 7

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016972.2NP_058668.1  large neutral amino acids transporter small subunit 2

    See identical proteins and their annotated locations for NP_058668.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059004
    Consensus CDS
    CCDS27101.1
    UniProtKB/Swiss-Prot
    Q9QXW9
    Related
    ENSMUSP00000022787.6, ENSMUST00000022787.7
    Conserved Domains (1) summary
    TIGR00911
    Location:1497
    2A0308; L-type amino acid transporter

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    54722215..54781886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519250.2XP_006519313.1  large neutral amino acids transporter small subunit 2 isoform X1

    Conserved Domains (1) summary
    TIGR00911
    Location:1295
    2A0308; L-type amino acid transporter
  2. XM_011245114.1XP_011243416.1  large neutral amino acids transporter small subunit 2 isoform X2

    Conserved Domains (1) summary
    pfam07895
    Location:169248
    DUF1673; Protein of unknown function (DUF1673)
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