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PKN1 protein kinase N1 [ Bos taurus (cattle) ]

Gene ID: 509080, updated on 13-Apr-2024

Summary

Official Symbol
PKN1provided by VGNC
Official Full Name
protein kinase N1provided by VGNC
Primary source
VGNC:VGNC:32945
See related
Ensembl:ENSBTAG00000017037
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (11304842..11333471, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene small EDRK-rich factor 1-like Neighboring gene DnaJ heat shock protein family (Hsp40) member B1 Neighboring gene GIPC PDZ domain containing family member 1 Neighboring gene prostaglandin E receptor 1 Neighboring gene DExD-box helicase 39A Neighboring gene adhesion G protein-coupled receptor E5

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC142408

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine/threonine-protein kinase N1
Names
protein kinase C-like 1
protein kinase C-like PKN
protein kinase PKN-alpha
protein-kinase C-related kinase 1
serine-threonine protein kinase N
NP_001073715.1
XP_024849826.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080246.1NP_001073715.1  serine/threonine-protein kinase N1

    See identical proteins and their annotated locations for NP_001073715.1

    Status: PROVISIONAL

    Source sequence(s)
    BC126539
    UniProtKB/Swiss-Prot
    A1A4I4
    UniProtKB/TrEMBL
    F1MFG6
    Related
    ENSBTAP00000074304.2, ENSBTAT00000070272.2
    Conserved Domains (6) summary
    cd08687
    Location:391477
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:4698
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11630
    Location:122197
    HR1_PKN1_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
    cd11636
    Location:206279
    HR1_PKN1_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
    smart00220
    Location:617876
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05589
    Location:617941
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    11304842..11333471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024994058.2XP_024849826.1  serine/threonine-protein kinase N1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LSW8, F1MFG6
    Related
    ENSBTAP00000099719.1, ENSBTAT00000107669.1
    Conserved Domains (5) summary
    cd08687
    Location:397483
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:52104
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11630
    Location:128203
    HR1_PKN1_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
    cd05589
    Location:623947
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:212285
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases