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IFNGR1 interferon gamma receptor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 508619, updated on 5-Sep-2025
Official Symbol
IFNGR1provided by VGNC
Official Full Name
interferon gamma receptor 1provided by VGNC
Primary source
VGNC:VGNC:30058
See related
BGD:BT12378; EnsemblRapid:ENSBTAG00070016902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See IFNGR1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (75081984..75106375, complement)

Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene interleukin 20 receptor subunit alpha Neighboring gene interleukin 22 receptor subunit alpha 2 Neighboring gene DDB1- and CUL4-associated factor 13-like Neighboring gene oligodendrocyte transcription factor 3

Genomic Sequence:
NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Microarray analysis of differentially expressed microRNAs in non-regressed and regressed bovine corpus luteum tissue; microRNA-378 may suppress luteal cell apoptosis by targeting the interferon gamma receptor 1 gene. Ma T, et al. J Appl Genet, 2011 Nov. PMID 21655975
  2. Identification of SNPs in interferon gamma, interleukin-22, and their receptors and associations with health and production-related traits in Canadian Holstein bulls. Verschoor CP, et al. Anim Biotechnol, 2011 Jan. PMID 21328101
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. analysis of mir-378 and of the interferon gamma receptor 1 protein at different stages of luteal development showed that mir-378 decreased the expression of interferon gamma receptor 1 protein but not the mRNA
    Title: Microarray analysis of differentially expressed microRNAs in non-regressed and regressed bovine corpus luteum tissue; microRNA-378 may suppress luteal cell apoptosis by targeting the interferon gamma receptor 1 gene.
  2. SNPs in IFNG, IFNGR1 and R2, IL22, and IL22RA1 were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
    Title: Identification of SNPs in interferon gamma, interleukin-22, and their receptors and associations with health and production-related traits in Canadian Holstein bulls.
Submit: New GeneRIF Correction

Homology

Clone Names

  • MGC129098

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in type II interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interferon gamma receptor 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035063.1 → NP_001030235.1  interferon gamma receptor 1 precursor

    See identical proteins and their annotated locations for NP_001030235.1

    Status: PROVISIONAL

    Source sequence(s)
    BC103296
    UniProtKB/TrEMBL
    Q05FF4, Q3ZBH1
    Related
    ENSBTAP00070022325.1, ENSBTAT00070037959.1
    Conserved Domains (2) summary
    pfam07140
    Location:158 → 313
    IFNGR1; Interferon gamma receptor (IFNGR1)
    cl21522
    Location:24 → 110
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    75081984..75106375 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059889619.1 → XP_059745602.1  interferon gamma receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MRC2

  2. XM_059889620.1 → XP_059745603.1  interferon gamma receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MRC2
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials