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PRODH2 proline dehydrogenase 2 [ Bos taurus (cattle) ]

Gene ID: 508542, updated on 5-Mar-2024

Summary

Official Symbol
PRODH2provided by VGNC
Official Full Name
proline dehydrogenase 2provided by VGNC
Primary source
VGNC:VGNC:33360
See related
BGD:BT12816; Ensembl:ENSBTAG00000031772
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
HYPDH
Orthologs
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Genomic context

Location:
chromosome: 18
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (46508441..46524659, complement)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 33 Neighboring gene inactive serine/threonine-protein kinase TEX14-like Neighboring gene U6 spliceosomal RNA Neighboring gene NPHS1 adhesion molecule, nephrin Neighboring gene kirre like nephrin family adhesion molecule 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables proline dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proline catabolic process to glutamate IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
hydroxyproline dehydrogenase
Names
probable proline dehydrogenase 2
probable proline oxidase 2
proline dehydrogenase (oxidase) 2
NP_001098437.1
XP_059732564.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104967.2NP_001098437.1  hydroxyproline dehydrogenase

    See identical proteins and their annotated locations for NP_001098437.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149682
    UniProtKB/Swiss-Prot
    A6QQ74
    UniProtKB/TrEMBL
    F1MZH9
    Related
    ENSBTAP00000042469.4, ENSBTAT00000045048.4
    Conserved Domains (2) summary
    PLN02681
    Location:28446
    PLN02681; proline dehydrogenase
    pfam01619
    Location:212439
    Pro_dh; Proline dehydrogenase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    46508441..46524659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059876581.1XP_059732564.1  hydroxyproline dehydrogenase isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LSL3