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ITGA3 integrin subunit alpha 3 [ Bos taurus (cattle) ]

Gene ID: 508490, updated on 26-Nov-2016
Gene symbol
ITGA3
Gene description
integrin subunit alpha 3
See related
Ensembl:ENSBTAG00000019498
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
GAPB3
Orthologs
Location:
chromosome: 19
Exon count:
26
Annotation release Status Assembly Chr Location
105 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 19 AC_000176.1 (37198635..37231287, complement)

Chromosome 19 - AC_000176.1Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 14 Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene distal-less homeobox 3 Neighboring gene uncharacterized LOC100196902 Neighboring gene distal-less homeobox 4

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Clone Names

  • MGC166158

Gene Ontology Provided by GOA

Function Evidence Code Pubs
glycoprotein binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protease binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
dendritic spine maintenance IEA
Inferred from Electronic Annotation
more info
 
exploration behavior IEA
Inferred from Electronic Annotation
more info
 
integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
lung development IEA
Inferred from Electronic Annotation
more info
 
memory IEA
Inferred from Electronic Annotation
more info
 
mesodermal cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
nephron development IEA
Inferred from Electronic Annotation
more info
 
neuron migration IEA
Inferred from Electronic Annotation
more info
 
positive regulation of establishment of protein localization to plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 
regulation of Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
regulation of transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
renal filtration IEA
Inferred from Electronic Annotation
more info
 
skin development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 
excitatory synapse IEA
Inferred from Electronic Annotation
more info
 
external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
filopodium membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
focal adhesion IEA
Inferred from Electronic Annotation
more info
 
integrin alpha3-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
invadopodium membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
synaptic membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
integrin alpha-3
Names
CD49 antigen-like family member C
Galactoprotein B3
Integrin alpha-3
VLA-3 subunit alpha
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
use the SwissProt name for F1MMS9

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302664.1NP_001289593.1  integrin alpha-3 precursor

    See identical proteins and their annotated locations for NP_001289593.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149926, BE479988, BF044715, BM430336, DN511524, DT894886, DV919812, DV920430, EE224462, EH180322
    UniProtKB/Swiss-Prot
    F1MMS9
    UniProtKB/TrEMBL
    A6QQN8
    Related
    ENSBTAP00000025974, ENSBTAT00000025974
    Conserved Domains (2) summary
    smart00191
    Location:366416
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:461915
    Integrin_alpha2; Integrin alpha

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1.1 Primary Assembly

Genomic

  1. AC_000176.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    37198635..37231287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_5.0.1

Genomic

  1. NC_007317.6 Alternate Btau_5.0.1

    Range
    37362097..37394749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001101900.1: Suppressed sequence

    Description
    NM_001101900.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: ITGA3 (GeneID:3675).
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