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TAS2R16 taste 2 receptor member 16 [ Homo sapiens (human) ]

Gene ID: 50833, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R16provided by HGNC
Official Full Name
taste 2 receptor member 16provided by HGNC
Primary source
HGNC:HGNC:14921
See related
Ensembl:ENSG00000128519 MIM:604867; AllianceGenome:HGNC:14921
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BGLPT; T2R16
Summary
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See TAS2R16 in Genome Data Viewer
Location:
7q31.32; 7q31
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (122994704..122995700, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (124311252..124312248, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (122634758..122635754, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene calcium dependent secretion activator 2 Neighboring gene RELA proto-oncogene, NF-kB subunit pseudogene Neighboring gene uncharacterized LOC105375482 Neighboring gene solute carrier family 13 member 1 Neighboring gene LYPLA1 pseudogene 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IC
Inferred by Curator
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
taste receptor type 2 member 16
Names
candidate taste receptor T2R16
taste receptor, type 2, member 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011980.1 RefSeqGene

    Range
    5001..5997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_016945.3NP_058641.1  taste receptor type 2 member 16

    See identical proteins and their annotated locations for NP_058641.1

    Status: REVIEWED

    Source sequence(s)
    AC004838, BC095524
    Consensus CDS
    CCDS5785.1
    UniProtKB/Swiss-Prot
    Q645W1, Q9NYV7
    UniProtKB/TrEMBL
    A0A8E5KFD5
    Related
    ENSP00000249284.2, ENST00000249284.3
    Conserved Domains (1) summary
    cd15017
    Location:8288
    7tm_TAS2R16; mammalian taste receptor 2, subtype 16, member of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    122994704..122995700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    124311252..124312248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)