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ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit [ Bos taurus (cattle) ]

Gene ID: 507984, updated on 8-Jul-2021

Summary

Official Symbol
ERCC3provided by VGNC
Official Full Name
ERCC excision repair 3, TFIIH core complex helicase subunitprovided by VGNC
Primary source
VGNC:VGNC:28570
See related
BGD:BT27157; Ensembl:ENSBTAG00000020777
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See ERCC3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 2 NC_037329.1 (5248748..5279068)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 2 AC_000159.1 (5181037..5211359)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene protein C, inactivator of coagulation factors Va and VIIIa Neighboring gene mitogen-activated protein kinase kinase kinase 2 Neighboring gene uncharacterized LOC101904564 Neighboring gene microRNA mir-2285aa Neighboring gene cytochrome P450, family 27, subfamily C, polypeptide 1 Neighboring gene 60S ribosomal protein L6 pseudogene

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Clone Names

  • MGC137777

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables promoter-specific chromatin binding IEA
Inferred from Electronic Annotation
more info
 
enables protein C-terminus binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein N-terminus binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in DNA repair ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in DNA topological change ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in UV protection IEA
Inferred from Electronic Annotation
more info
 
involved_in apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in hair cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nucleotide-excision repair ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nucleotide-excision repair, DNA duplex unwinding ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nucleotide-excision repair, DNA incision ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of mitotic cell cycle phase transition ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to UV ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to oxidative stress ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transcription elongation from RNA polymerase I promoter IEA
Inferred from Electronic Annotation
more info
 
involved_in transcription-coupled nucleotide-excision repair ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
 
part_of transcription factor TFIIH core complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
general transcription and DNA repair factor IIH helicase subunit XPB
Names
DNA excision repair protein ERCC-3
TFIIH basal transcription factor complex helicase XPB subunit
TFIIH subunit XPB
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
NP_001039453.1
XP_015329897.1
XP_024855871.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045988.1NP_001039453.1  general transcription and DNA repair factor IIH helicase subunit XPB

    See identical proteins and their annotated locations for NP_001039453.1

    Status: PROVISIONAL

    Source sequence(s)
    BC114729
    UniProtKB/Swiss-Prot
    Q1RMT1
    Related
    ENSBTAP00000027687.4, ENSBTAT00000027687.5
    Conserved Domains (1) summary
    TIGR00603
    Location:60779
    rad25; DNA repair helicase rad25

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    5248748..5279068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015474411.2XP_015329897.1  general transcription and DNA repair factor IIH helicase subunit XPB isoform X1

    Conserved Domains (1) summary
    TIGR00603
    Location:1715
    rad25; DNA repair helicase rad25
  2. XM_025000103.1XP_024855871.1  general transcription and DNA repair factor IIH helicase subunit XPB isoform X1

    Conserved Domains (1) summary
    TIGR00603
    Location:1715
    rad25; DNA repair helicase rad25
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