INPP5D inositol polyphosphate-5-phosphatase D [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: INPP5Dprovided by VGNC
Official Full Name: inositol polyphosphate-5-phosphatase Dprovided by VGNC
Primary source: VGNC:VGNC:30212
See related: BGD:BT17527; EnsemblRapid:ENSBTAG00070002643
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (112794197..112931953)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of bone resorption	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of neutrophil differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

Names: SH2 containing inositol phosphatase; inositol polyphosphate-5-phosphatase, 145kDa

NP_001095352.1

EC 3.1.3.86

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101882.2 → NP_001095352.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

See identical proteins and their annotated locations for NP_001095352.1

Status: PROVISIONAL

Source sequence(s)

BC151609

UniProtKB/TrEMBL

A0A3Q1LJT8, A7MBK3, F6QCI5

Related

ENSBTAP00070003537.1, ENSBTAT00070006110.1

Conserved Domains (2) summary

cd09100
Location:404 → 710

INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins

cd10343
Location:1 → 102

SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)