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CARS2 cysteinyl-tRNA synthetase 2, mitochondrial [ Bos taurus (domestic cattle) ]

Gene ID: 506598, updated on 18-Aug-2024

Summary

Official Symbol
CARS2provided by VGNC
Official Full Name
cysteinyl-tRNA synthetase 2, mitochondrialprovided by VGNC
Primary source
VGNC:VGNC:49547
See related
BGD:BT29180; Ensembl:ENSBTAG00000011471
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

Location:
chromosome: 12
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (85239190..85268251, complement)

Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene RAB20, member RAS oncogene family Neighboring gene uncharacterized LOC132346802 Neighboring gene NAD(P)HX dehydratase Neighboring gene inhibitor of growth family member 1 Neighboring gene uncharacterized LOC132346803 Neighboring gene ankyrin repeat domain 10 Neighboring gene uncharacterized LOC112449091 Neighboring gene uncharacterized LOC112449092

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

General gene information

Clone Names

  • MGC137370

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cysteine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cysteinyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cysteine--tRNA ligase, mitochondrial
Names
cysRS
cysteine--tRNA ligase, mitochondrial-like
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
cysteinyl-tRNA synthetase, mitochondrial
probable cysteinyl-tRNA synthetase, mitochondrial
NP_001039409.1
XP_010809278.1
XP_024855567.1
XP_024855569.1
XP_024855570.2
XP_059747973.1
XP_059747974.1
XP_059747975.1
XP_059747976.1
XP_059747977.1
XP_059747978.1
XP_059747979.1
XP_059747980.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045944.2NP_001039409.1  cysteine--tRNA ligase, mitochondrial

    See identical proteins and their annotated locations for NP_001039409.1

    Status: PROVISIONAL

    Source sequence(s)
    BC112654
    UniProtKB/Swiss-Prot
    Q2KIF8
    UniProtKB/TrEMBL
    A0AAA9SEB2
    Related
    ENSBTAP00000083737.1, ENSBTAT00000126133.1
    Conserved Domains (2) summary
    cd00672
    Location:45348
    CysRS_core; catalytic core domain of cysteinyl tRNA synthetase
    COG0215
    Location:45544
    CysS; Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    85239190..85268251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059891995.1XP_059747978.1  cysteine--tRNA ligase, mitochondrial isoform X8

    UniProtKB/TrEMBL
    A0AAA9SEB2
  2. XM_059891997.1XP_059747980.1  cysteine--tRNA ligase, mitochondrial isoform X12

  3. XM_059891994.1XP_059747977.1  cysteine--tRNA ligase, mitochondrial isoform X6

    UniProtKB/TrEMBL
    A0AAA9SEB2
  4. XM_059891996.1XP_059747979.1  cysteine--tRNA ligase, mitochondrial isoform X10

  5. XM_059891992.1XP_059747975.1  cysteine--tRNA ligase, mitochondrial isoform X3

  6. XM_059891991.1XP_059747974.1  cysteine--tRNA ligase, mitochondrial isoform X2

  7. XM_059891990.1XP_059747973.1  cysteine--tRNA ligase, mitochondrial isoform X1

  8. XM_024999802.2XP_024855570.2  cysteine--tRNA ligase, mitochondrial isoform X4

  9. XM_024999799.2XP_024855567.1  cysteine--tRNA ligase, mitochondrial isoform X7

    UniProtKB/TrEMBL
    A0A3Q1NB71, A0AAA9SEB2
    Related
    ENSBTAP00000068554.2, ENSBTAT00000078522.2
    Conserved Domains (1) summary
    cl27478
    Location:27535
    tRNA-synt_1e; tRNA synthetases class I (C) catalytic domain
  10. XM_024999801.2XP_024855569.1  cysteine--tRNA ligase, mitochondrial isoform X9

    Conserved Domains (1) summary
    cl27478
    Location:53462
    tRNA-synt_1e; tRNA synthetases class I (C) catalytic domain
  11. XM_010810976.4XP_010809278.1  cysteine--tRNA ligase, mitochondrial isoform X11

    Conserved Domains (2) summary
    COG0215
    Location:20432
    CysS; Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    cl00015
    Location:20245
    nt_trans; nucleotidyl transferase superfamily
  12. XM_059891993.1XP_059747976.1  cysteine--tRNA ligase, mitochondrial isoform X5