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Ptk2b protein tyrosine kinase 2 beta [ Rattus norvegicus (Norway rat) ]

Gene ID: 50646, updated on 9-Oct-2018

Summary

Official Symbol
Ptk2bprovided by RGD
Official Full Name
protein tyrosine kinase 2 betaprovided by RGD
Primary source
RGD:628758
See related
Ensembl:ENSRNOG00000027839
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
CAKB; Pyk2; CAKbeta; CAK beta
Summary
may phosphorylate focal adhesion kinase FAK; may play a role in actin cytoskeleton reorganization; may mediate thrombin induced astrocyte proliferation [RGD, Feb 2006]
Expression
Biased expression in Spleen (RPKM 94.7), Thymus (RPKM 82.2) and 9 other tissues See more
Orthologs

Genomic context

See Ptk2b in Genome Data Viewer
Location:
15p12
Exon count:
35
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (42827306..42947796, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 15 NC_005114.3 (48646476..48766708)

Chromosome 15 - NC_005114.4Genomic Context describing neighboring genes Neighboring gene epoxide hydrolase 2 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene microRNA 6320 Neighboring gene tripartite motif-containing 35

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC124628

Gene Ontology Provided by RGD

Function Evidence Code Pubs
3-phosphoinositide-dependent protein kinase binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to NMDA glutamate receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
calmodulin-dependent protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
non-membrane spanning protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
non-membrane spanning protein tyrosine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein C-terminus binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin filament organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of Janus kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of Janus kinase activity ISO
Inferred from Sequence Orthology
more info
 
adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel endothelial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
bone resorption ISO
Inferred from Sequence Orthology
more info
 
bone resorption ISS
Inferred from Sequence or Structural Similarity
more info
 
cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
cell surface receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular defense response IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to fluid shear stress IEA
Inferred from Electronic Annotation
more info
 
cellular response to fluid shear stress ISO
Inferred from Sequence Orthology
more info
 
cellular response to retinoic acid IEA
Inferred from Electronic Annotation
more info
 
cellular response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
chemokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemokine-mediated signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
epidermal growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
focal adhesion assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
glial cell proliferation IEP
Inferred from Expression Pattern
more info
PubMed 
integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
integrin-mediated signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
ionotropic glutamate receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-term synaptic depression IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
marginal zone B cell differentiation ISO
Inferred from Sequence Orthology
more info
 
marginal zone B cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of bone mineralization ISO
Inferred from Sequence Orthology
more info
 
negative regulation of bone mineralization ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of muscle cell apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of myeloid cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of myeloid cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of ossification IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
oocyte maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
peptidyl-tyrosine autophosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-tyrosine autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-tyrosine autophosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
peptidyl-tyrosine autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of B cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of B cell chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of DNA biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ERK1 and ERK2 cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of JNK cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of JNK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of JUN kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of actin filament polymerization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of actin filament polymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell-matrix adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cellular protein metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cytosolic calcium ion concentration IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of endothelial cell migration IEA
Inferred from Electronic Annotation
more info
 
positive regulation of endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of excitatory postsynaptic potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of nitric oxide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of nitric-oxide synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of nitric-oxide synthase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phosphatidylinositol 3-kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phosphatidylinositol 3-kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
regulation of NMDA receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of actin cytoskeleton reorganization ISO
Inferred from Sequence Orthology
more info
 
regulation of actin cytoskeleton reorganization ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
regulation of cGMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
regulation of calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
regulation of cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
regulation of cell shape ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of establishment of cell polarity ISO
Inferred from Sequence Orthology
more info
 
regulation of establishment of cell polarity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of inositol trisphosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
regulation of inositol trisphosphate biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of macrophage chemotaxis ISO
Inferred from Sequence Orthology
more info
 
regulation of macrophage chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
regulation of release of sequestered calcium ion into cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
response to cAMP IEP
Inferred from Expression Pattern
more info
PubMed 
response to calcium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to cocaine IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucose IEP
Inferred from Expression Pattern
more info
PubMed 
response to hormone IEP
Inferred from Expression Pattern
more info
PubMed 
response to hydrogen peroxide IPI
Inferred from Physical Interaction
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
response to immobilization stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to lithium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
response to organonitrogen compound IEP
Inferred from Expression Pattern
more info
PubMed 
response to osmotic stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to reactive oxygen species IEP
Inferred from Expression Pattern
more info
PubMed 
signal complex assembly IEA
Inferred from Electronic Annotation
more info
 
sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
sprouting angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
stress fiber assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
tumor necrosis factor-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
vascular endothelial growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
NMDA selective glutamate receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
NMDA selective glutamate receptor complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
apical dendrite IDA
Inferred from Direct Assay
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
PubMed 
cell body IDA
Inferred from Direct Assay
more info
PubMed 
cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
cell projection IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
growth cone IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISS
Inferred from Sequence or Structural Similarity
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
postsynapse IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein-tyrosine kinase 2-beta
Names
CADTK
CAK-beta
FADK 2
PTK2 protein tyrosine kinase 2 beta
PTK2B protein tyrosine kinase 2 beta
calcium-dependent tyrosine kinase
calcium-regulated non-receptor proline-rich tyrosine kinase
cell adhesion kinase beta
focal adhesion kinase 2
proline-rich tyrosine kinase 2
NP_059014.2
XP_006252205.1
XP_006252206.1
XP_006252207.1
XP_008768995.1
XP_008768996.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017318.2NP_059014.2  protein-tyrosine kinase 2-beta

    See identical proteins and their annotated locations for NP_059014.2

    Status: PROVISIONAL

    Source sequence(s)
    BC101921
    UniProtKB/Swiss-Prot
    P70600
    Related
    ENSRNOP00000031615.1, ENSRNOT00000030007.3
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005114.4 Reference Rnor_6.0 Primary Assembly

    Range
    42827306..42947796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006252145.3XP_006252207.1  protein-tyrosine kinase 2-beta isoform X2

    UniProtKB/Swiss-Prot
    P70600
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:830959
    Focal_AT; Focal adhesion targeting region
  2. XM_006252144.3XP_006252206.1  protein-tyrosine kinase 2-beta isoform X1

    See identical proteins and their annotated locations for XP_006252206.1

    UniProtKB/Swiss-Prot
    P70600
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region
  3. XM_006252143.3XP_006252205.1  protein-tyrosine kinase 2-beta isoform X1

    See identical proteins and their annotated locations for XP_006252205.1

    UniProtKB/Swiss-Prot
    P70600
    Related
    ENSRNOP00000036813.4, ENSRNOT00000030036.4
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region
  4. XM_008770773.2XP_008768995.1  protein-tyrosine kinase 2-beta isoform X1

    See identical proteins and their annotated locations for XP_008768995.1

    UniProtKB/Swiss-Prot
    P70600
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region
  5. XM_008770774.2XP_008768996.1  protein-tyrosine kinase 2-beta isoform X1

    See identical proteins and their annotated locations for XP_008768996.1

    UniProtKB/Swiss-Prot
    P70600
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region

Alternate Rn_Celera

Genomic

  1. AC_000083.1 Alternate Rn_Celera

    Range
    40034001..40153993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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