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WRN Werner syndrome RecQ like helicase [ Bos taurus (cattle) ]

Gene ID: 505061, updated on 2-Apr-2017
Gene symbol
WRN
Gene description
Werner syndrome RecQ like helicase
See related
Ensembl:ENSBTAG00000021592
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Annotation information
Annotation category: partial on reference assembly
Orthologs
Location:
chromosome: 27
Exon count:
34
Annotation release Status Assembly Chr Location
105 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 27 AC_000184.1 (26263003..26326100) , (26392541..26449795)

Chromosome 27 - AC_000184.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101906615 Neighboring gene purine rich element binding protein G Neighboring gene uncharacterized LOC104976093 Neighboring gene neuregulin 1

Markers

Homology

Preferred Names
Werner syndrome ATP-dependent helicase
Names
Werner syndrome, RecQ helicase-like
NP_001137329.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143857.2NP_001137329.2  Werner syndrome ATP-dependent helicase

    Status: PROVISIONAL

    Source sequence(s)
    AAFC02040296, AAFC03085827, AAFC03085828, AAFC03085829, AAFC03085830, BF075592, BI680560, CK975716, CK976011, DN531055, DN532432, DY106259, DY137570, EE354110, GH316016
    Related
    ENSBTAP00000028778.5, ENSBTAT00000028778.5
    Conserved Domains (8) summary
    smart00341
    Location:11171195
    HRDC; Helicase and RNase D C-terminal
    TIGR00614
    Location:504976
    recQ_fam; ATP-dependent DNA helicase, RecQ family
    cd06129
    Location:59226
    RNaseD_like; DEDDy 3'-5' exonuclease domain of RNase D, WRN, and similar proteins
    smart00956
    Location:9241017
    RQC; This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure
    cd00079
    Location:700834
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:517678
    DEAD; DEAD/DEAH box helicase
    pfam14493
    Location:12271316
    HTH_40; Helix-turn-helix domain
    pfam16124
    Location:839906
    RecQ_Zn_bind; RecQ zinc-binding

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1.1 Primary Assembly

Genomic

  1. AC_000184.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    26263003..26326100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. AC_000184.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    26392541..26449795
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_5.0.1

Genomic

  1. NC_007328.5 Alternate Btau_5.0.1

    Range
    26408375..26632606
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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