Format

Send to:

Choose Destination

G0S2 G0/G1 switch 2 [ Homo sapiens (human) ]

Gene ID: 50486, updated on 7-Jun-2020

Summary

Official Symbol
G0S2provided by HGNC
Official Full Name
G0/G1 switch 2provided by HGNC
Primary source
HGNC:HGNC:30229
See related
Ensembl:ENSG00000123689 MIM:614447
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in fat (RPKM 569.0), bone marrow (RPKM 395.4) and 4 other tissues See more
Orthologs

Genomic context

See G0S2 in Genome Data Viewer
Location:
1q32.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (209675412..209676390)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (209848670..209849735)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985256 Neighboring gene calcium/calmodulin dependent protein kinase IG Neighboring gene laminin subunit beta 3 Neighboring gene microRNA 4260 Neighboring gene HSD11B1 antisense RNA 1 Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 Neighboring gene adenosine A2b receptor pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope transmembrane glycoprotein gp41 env A synthetic peptide corresponding to the immunosuppressive domain (amino acids 574-592) of HIV-1 gp41 upregulates the expression of G0/G1switch 2 (G0S2) in peptide-treated PBMCs PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
lipid droplet TAS
Traceable Author Statement
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
G0/G1 switch protein 2
Names
G0/G1 switch regulatory protein 2
G0/G1switch 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015714.4NP_056529.1  G0/G1 switch protein 2

    See identical proteins and their annotated locations for NP_056529.1

    Status: VALIDATED

    Source sequence(s)
    AV709160, BM788126
    Consensus CDS
    CCDS1488.1
    UniProtKB/Swiss-Prot
    P27469
    Related
    ENSP00000355996.4, ENST00000367029.5
    Conserved Domains (1) summary
    pfam15103
    Location:1103
    G0-G1_switch_2; G0/G1 switch protein 2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    209675412..209676390
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center