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trpt1 tRNA phosphotransferase 1 [ Danio rerio (zebrafish) ]

Gene ID: 503604, updated on 20-Feb-2026
Official Symbol
trpt1provided by ZNC
Official Full Name
tRNA phosphotransferase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050227-16
See related
Ensembl:ENSDARG00000037628 AllianceGenome:ZFIN:ZDB-GENE-050227-16
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:113138
Summary
Predicted to enable tRNA 2'-phosphotransferase activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to act upstream of or within tRNA processing. Orthologous to human TRPT1 (tRNA phosphotransferase 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
all
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See trpt1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 14 NC_133189.1 (7670523..7681131, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 14 NC_007125.7 (7131008..7137783, complement)

Chromosome 14 - NC_133189.1Genomic Context describing neighboring genes Neighboring gene heparin-binding EGF-like growth factor a Neighboring gene si:ch73-43g23.1 Neighboring gene uncharacterized LOC141377679 Neighboring gene cathepsin F Neighboring gene storkhead box 2b Neighboring gene uncharacterized LOC141377683

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables tRNA 2'-phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA 2'-phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA splicing, via endonucleolytic cleavage and ligation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
Preferred Names
tRNA 2'-phosphotransferase 1
NP_001013309.2
XP_068069302.1
XP_073777491.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013291.3 → NP_001013309.2  tRNA 2'-phosphotransferase 1

    See identical proteins and their annotated locations for NP_001013309.2

    Status: PROVISIONAL

    Source sequence(s)
    BC090282
    UniProtKB/Swiss-Prot
    Q5EAR5
    UniProtKB/TrEMBL
    A0AC58H686
    Related
    ENSDARP00000054802.5, ENSDART00000054803.7
    Conserved Domains (1) summary
    pfam01885
    Location:25 → 197
    PTS_2-RNA; RNA 2'-phosphotransferase, Tpt1 / KptA family

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133189.1 Reference GRCz12tu Primary Assembly

    Range
    7670523..7681131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073921390.1 → XP_073777491.1  tRNA 2'-phosphotransferase 1 isoform X2

    UniProtKB/Swiss-Prot
    Q5EAR5
    UniProtKB/TrEMBL
    A0AC58H686

  2. XM_068213201.2 → XP_068069302.1  tRNA 2'-phosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0AB32T7C7
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5EAR5.2 GenPept UniProtKB/Swiss-Prot:Q5EAR5

Gene LinkOut

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