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Tmem229b transmembrane protein 229B [ Rattus norvegicus (Norway rat) ]

Gene ID: 503035, updated on 16-Jun-2026
Official Symbol
Tmem229bprovided by RGD
Official Full Name
transmembrane protein 229Bprovided by RGD
Primary source
RGD:1562622
See related
Ensembl:ENSRNOG00000010646 AllianceGenome:RGD:1562622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562622
Summary
Predicted to act upstream of or within macrophage activation and response to bacterium. Predicted to be located in membrane. Orthologous to human TMEM229B (transmembrane protein 229B). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Thymus (RPKM 133.5), Spleen (RPKM 112.6) and 9 other tissues See more
Orthologs
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Try the new Transcripts and proteins table
See Tmem229b in Genome Data Viewer
Location:
6q24
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (103509457..103552600, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (97771645..97819582, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (102152146..102196372, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene pleckstrin 2 Neighboring gene uncharacterized LOC102547797 Neighboring gene pleckstrin homology, MyTH4 and FERM domain containing H1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class H Neighboring gene branched chain ketoacid dehydrogenase kinase, pseudogene 1

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
transmembrane protein 229B

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001434333.1NP_001421262.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3
  2. NM_001434334.1NP_001421263.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3
  3. NM_001434336.1NP_001421265.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3
  4. NM_001434337.1NP_001421266.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3
  5. NM_001434338.1NP_001421267.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3
  6. NM_001434339.1NP_001421268.1  transmembrane protein 229B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4ACC3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    103509457..103552600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594316.2XP_017449805.1  

    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  2. XM_017594325.3XP_017449814.1  

    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  3. XM_017594319.3XP_017449808.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
    Related
    ENSRNOP00000100204.1, ENSRNOT00000137203.1
    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  4. XM_017594313.3XP_017449802.1  

    Related
    ENSRNOP00000097942.1, ENSRNOT00000119192.2
    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  5. XM_063262352.1XP_063118422.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
  6. XM_063262349.1XP_063118419.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
    Related
    ENSRNOP00000014132.2, ENSRNOT00000014132.6
  7. XM_063262351.1XP_063118421.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
    Related
    ENSRNOP00000086127.1, ENSRNOT00000098038.2
  8. XM_063262350.1XP_063118420.1  

  9. XM_063262348.1XP_063118418.1  

  10. XM_017594315.3XP_017449804.1  

    Related
    ENSRNOP00000102485.1, ENSRNOT00000150319.1
    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  11. XM_039112767.2XP_038968695.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV
  12. XM_039112770.2XP_038968698.1  transmembrane protein 229B isoform X1

    UniProtKB/TrEMBL
    D4ACC3
    Related
    ENSRNOP00000110994.1, ENSRNOT00000147886.1
    Conserved Domains (1) summary
    cl26964
    Location:50135
    ABC_trans_CmpB; Putative ABC-transporter type IV

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001109359.2: Suppressed sequence

    Description
    NM_001109359.2: This RefSeq was removed because currently there is no support for the transcript.