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Cpa4 carboxypeptidase A4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502736, updated on 2-Oct-2018

Summary

Official Symbol
Cpa4provided by RGD
Official Full Name
carboxypeptidase A4provided by RGD
Primary source
RGD:1563619
See related
Ensembl:ENSRNOG00000010463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563619
Expression
Biased expression in Lung (RPKM 13.7), Testes (RPKM 6.5) and 6 other tissues See more
Orthologs

Genomic context

See Cpa4 in Genome Data Viewer
Location:
4q22
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (57883849..57907826)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (57644770..57668743)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene serine-rich single-pass membrane protein 1 Neighboring gene carboxypeptidase A2 Neighboring gene uncharacterized LOC108350686 Neighboring gene uncharacterized LOC102553416 Neighboring gene carboxypeptidase A5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
metallocarboxypeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109346.2NP_001102816.1  carboxypeptidase A4 precursor

    See identical proteins and their annotated locations for NP_001102816.1

    Status: VALIDATED

    Source sequence(s)
    AC107243
    UniProtKB/TrEMBL
    D3ZHS5
    Related
    ENSRNOP00000013880.3, ENSRNOT00000013880.5
    Conserved Domains (2) summary
    pfam02244
    Location:2899
    Propep_M14; Carboxypeptidase activation peptide
    cl11393
    Location:117419
    Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    57883849..57907826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    54286758..54310882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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