U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Faap24 FA core complex associated protein 24 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502320, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Faap24provided by RGD
Official Full Name
FA core complex associated protein 24provided by RGD
Primary source
RGD:1564719
See related
Ensembl:ENSRNOG00000022393 AllianceGenome:RGD:1564719
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564719
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in interstrand cross-link repair. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Orthologous to human FAAP24 (FA core complex associated protein 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 40.9), Kidney (RPKM 39.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Faap24 in Genome Data Viewer
Location:
1q21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (97188678..97194899, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (88051523..88057997, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (91657263..91663485, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene G patch domain containing 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G like 1 Neighboring gene rhophilin, Rho GTPase binding protein 2 Neighboring gene centrosomal protein 89 Neighboring gene solute carrier family 7 member 9

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Singh TR, et al. Mol Cell, 2010 Mar 26. PMID 20347429, Free PMC Article
  2. A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Yan Z, et al. Mol Cell, 2010 Mar 26. PMID 20347428, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in interstrand cross-link repair ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of FANCM-MHF complex ISO
Inferred from Sequence Orthology
more info
  
part_of Fanconi anaemia nuclear complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Fanconi anaemia nuclear complex ISO
Inferred from Sequence Orthology
more info
  
part_of chromatin ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Fanconi anemia core complex-associated protein 24
Names
Fanconi anemia core complex associated protein 24
Fanconi anemia-associated protein of 24 kDa

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109335.1 → NP_001102805.1  Fanconi anemia core complex-associated protein 24

    See identical proteins and their annotated locations for NP_001102805.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A6JAA9, D3ZE71
    Conserved Domains (1) summary
    pfam12826
    Location:166 → 218
    HHH_2; Helix-hairpin-helix motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    97188678..97194899 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088338.2 → XP_038944266.1  Fanconi anemia core complex-associated protein 24 isoform X2

    Conserved Domains (2) summary
    pfam12826
    Location:98 → 150
    HHH_2; Helix-hairpin-helix motif
    cl41760
    Location:14 → 71
    XPF_nuclease-like; nuclease domain of XPF/MUS81 family proteins

  2. XM_006228896.5 → XP_006228958.1  Fanconi anemia core complex-associated protein 24 isoform X1

    See identical proteins and their annotated locations for XP_006228958.1

    UniProtKB/TrEMBL
    A6JAA9, D3ZE71
    Related
    ENSRNOP00000031862.3
    Conserved Domains (1) summary
    pfam12826
    Location:166 → 218
    HHH_2; Helix-hairpin-helix motif
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous