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BomS3 Bomanin Short 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50209, updated on 6-Jul-2026
Official Symbol
BomS3provided by FlyBase
Official Full Name
Bomanin Short 3provided by FlyBase
Primary source
FLYBASE:FBgn0040736
Locus tag
Dmel_CG16844
See related
AllianceGenome:FB:FBgn0040736
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH58911; Bom3; CG16844; CT37419; DIM 3; DIM3; Dmel\CG16844; im3; IM3
Summary
Involved in antibacterial humoral response; defense response to Gram-positive bacterium; and response to mycotoxin. Located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Try the new Transcripts and proteins table
See BomS3 in Genome Data Viewer
Location:
55C4-55C4; 2-85 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18387895..18388734)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14275400..14276239)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2 Neighboring gene Bomanin Short 2 Neighboring gene Bomanin Tailed 2 Neighboring gene Bomanin Short 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The Daisho Peptides Mediate Drosophila Defense Against a Subset of Filamentous Fungi. Cohen LB, et al. Front Immunol, 2020. PMID 32038657, Free PMC Article
  2. Polyphenol extracts from rambutan peel promote longevity via the attenuation of the Toll/Imd pathway. Huang JC, et al. Food Funct, 2025 Mar 31. PMID 40094275
  3. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
  4. Chronic exposure to the star polycation (SPc) nanocarrier in the larval stage adversely impairs life history traits in Drosophila melanogaster. Yan S, et al. J Nanobiotechnology, 2022 Dec 8. PMID 36482441, Free PMC Article
  5. Evolution of resistance and disease tolerance mechanisms to oral bacterial infection in Drosophila melanogaster. Paulo TF, et al. Open Biol, 2025 Mar. PMID 40068814, Free PMC Article

See all (104) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in antibacterial humoral response IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to Gram-positive bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to bacterium HEP PubMed 
involved_in response to mycotoxin IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region EXP
Inferred from Experiment
more info
 PubMed 
is_active_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
bomanin short 3
Names
BomS3-PA
BomS3-PB
CG16844-PA
CG16844-PB
bomanin 3
bomanin S3
immune induced molecule 3

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18387895..18388734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299640.1 → NP_001286569.1  bomanin short 3, isoform B

    See identical proteins and their annotated locations for NP_001286569.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V8G0
    UniProtKB/TrEMBL
    A0A0B4LGW9, A0A1B2AJ12
    Conserved Domains (1) summary
    pfam08194
    Location:1 → 36
    DIM; DIM protein

  2. NM_144111.3 → NP_652368.1  bomanin short 3, isoform A

    See identical proteins and their annotated locations for NP_652368.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V8G0
    UniProtKB/TrEMBL
    A0A0B4LGW9, A0A1B2AJ12
    Related
    FBpp0085846
    Conserved Domains (1) summary
    pfam08194
    Location:1 → 36
    DIM; DIM protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LGW9 A0A0B4LGW9
Q8IGC3 Q8IGC3
Q9V8G0.1 Q9V8G0

Gene LinkOut

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