Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cmtm7provided by RGD
Official Full Name: CKLF-like MARVEL transmembrane domain containing 7provided by RGD
Primary source: RGD:1591926
See related: Ensembl:ENSRNOG00000067317 AllianceGenome:RGD:1591926
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cklfsf7
Summary: Predicted to act upstream of or within B-1a B cell differentiation. Predicted to be active in membrane. Orthologous to human CMTM7 (CKLF like MARVEL transmembrane domain containing 7). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Thymus (RPKM 130.9), Spleen (RPKM 85.1) and 9 other tissues See more
Orthologs: all
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Genomic context

Location:: 8q32

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (123326233..123353148, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (114448037..114474958, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (122814563..122841479, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129264 (e-PCR)
- UniSTS:212571

RH129273 (e-PCR)
- UniSTS:212580

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within B cell activation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within B-1a B cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within inflammatory response to antigenic stimulus	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within plasma cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of p38MAPK cascade	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein phosphorylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within toll-like receptor signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CKLF-like MARVEL transmembrane domain-containing protein 7

Names: chemokine-like factor super family 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.