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Isocitrate/isopropylmalate dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 5007861, updated on 6-Jul-2026
Official Full Name
Isocitrate/isopropylmalate dehydrogenase family protein
Primary source
TAIR:AT1G80555
Locus tag
AT1G80555
See related
Araport:AT1G80555
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (30286956..30287741)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene envelope glycoprotein B Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene isopropylmalate dehydrogenase 2 Neighboring gene RNI-like superfamily protein

Genomic Sequence:
NC_003070.9
NM_001084388.2
NM_001334994.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-isopropylmalate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in L-leucine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
 
Preferred Names
Isocitrate/isopropylmalate dehydrogenase family protein
NP_001077857.1
  • Isocitrate/isopropylmalate dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, 3-isopropylmalate dehydrogenase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, magnesium ion binding; INVOLVED IN: oxidation reduction, leucine biosynthetic process; LOCATED IN: chloroplast, cytoplasm; CONTAINS InterPro DOMAIN/s: Isopropylmalate dehydrogenase (InterPro:IPR004429), Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804); BEST Arabidopsis thaliana protein match is: isopropylmalate dehydrogenase 1 (TAIR:AT5G14200.1); Has 7334 Blast hits to 7334 proteins in 2186 species: Archae - 214; Bacteria - 4706; Metazoa - 4; Fungi - 440; Plants - 78; Viruses - 0; Other Eukaryotes - 1892 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    30286956..30287741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001084388.2NP_001077857.1  Isocitrate/isopropylmalate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077857.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4HTY6, Q1G324
    Conserved Domains (1) summary
    cl00445
    Location:12115
    Iso_dh; Isocitrate/isopropylmalate dehydrogenase
  2. NM_001334994.1NP_001322191.1  Isocitrate/isopropylmalate dehydrogenase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AT86