Format

Send to:

Choose Destination

Tra2a transformer 2 alpha homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 500116, updated on 5-Jan-2022

Summary

Official Symbol
Tra2aprovided by RGD
Official Full Name
transformer 2 alpha homologprovided by RGD
Primary source
RGD:1562563
See related
Ensembl:ENSRNOG00000009156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562563
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in mRNA splicing, via spliceosome and positive regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human TRA2A (transformer 2 alpha homolog). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Thymus (RPKM 205.6), Spleen (RPKM 152.9) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tra2a in Genome Data Viewer
Location:
4q24
Exon count:
8
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (78220838..78239737, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78905380..78924203, complement)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene mitochondrial assembly of ribosomal large subunit 1 Neighboring gene insulin-like growth factor 2 mRNA binding protein 3 Neighboring gene uncharacterized LOC120102265 Neighboring gene gem (nuclear organelle) associated protein 7-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transformer-2 protein homolog alpha

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126296.2NP_001119768.2  transformer-2 protein homolog alpha

    See identical proteins and their annotated locations for NP_001119768.2

    Status: VALIDATED

    Source sequence(s)
    BC161978, JACYVU010000142
    UniProtKB/TrEMBL
    B1WC25
    Conserved Domains (1) summary
    cd12363
    Location:116195
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    78220838..78239737 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236466.4XP_006236528.1  transformer-2 protein homolog alpha isoform X4

    Conserved Domains (1) summary
    cd12363
    Location:116195
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
  2. XM_006236465.4XP_006236527.1  transformer-2 protein homolog alpha isoform X3

    See identical proteins and their annotated locations for XP_006236527.1

    Conserved Domains (1) summary
    cd12363
    Location:116195
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
  3. XM_006236464.4XP_006236526.1  transformer-2 protein homolog alpha isoform X2

    Conserved Domains (1) summary
    cd12363
    Location:116195
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
  4. XM_017592791.2XP_017448280.1  transformer-2 protein homolog alpha isoform X5

    Conserved Domains (1) summary
    cd12363
    Location:1796
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
  5. XM_017592792.2XP_017448281.1  transformer-2 protein homolog alpha isoform X5

    Conserved Domains (1) summary
    cd12363
    Location:1796
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
  6. XM_039108127.1XP_038964055.1  transformer-2 protein homolog alpha isoform X1

    Related
    ENSRNOP00000012325.8, ENSRNOT00000012325.8
    Conserved Domains (1) summary
    cd12363
    Location:116195
    RRM_TRA2; RNA recognition motif (RRM) found in transformer-2 protein homolog TRA2-alpha, TRA2-beta and similar proteins
Support Center