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Clca4l chloride channel calcium activated 4-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 499721, updated on 2-Oct-2018

Summary

Official Symbol
Clca4lprovided by RGD
Official Full Name
chloride channel calcium activated 4-likeprovided by RGD
Primary source
RGD:1591945
See related
Ensembl:ENSRNOG00000036877
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rbclca2
Expression
Biased expression in Testes (RPKM 11.3), Spleen (RPKM 5.0) and 7 other tissues See more

Genomic context

See Clca4l in Genome Data Viewer
Location:
2q44
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (250785534..250805445, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (269312355..269332154, complement)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene SH3 domain -containing GRB2-like endophilin B1 Neighboring gene chloride channel calcium activated 2 Neighboring gene uncharacterized LOC108350129 Neighboring gene uncharacterized LOC102549543 Neighboring gene chloride channel accessory 4 Neighboring gene chloride channel accessory 1 Neighboring gene uncharacterized LOC108350130

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Pathways from BioSystems

  • Pancreatic secretion, organism-specific biosystem (from KEGG)
    Pancreatic secretion, organism-specific biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Pancreatic secretion, conserved biosystem (from KEGG)
    Pancreatic secretion, conserved biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Renin secretion, organism-specific biosystem (from KEGG)
    Renin secretion, organism-specific biosystemThe aspartyl-protease renin is the key regulator of the renin-angiotensin-aldosterone system, which is critically involved in extracellular fluid volume and blood pressure homeostasis of the body. R...
  • Renin secretion, conserved biosystem (from KEGG)
    Renin secretion, conserved biosystemThe aspartyl-protease renin is the key regulator of the renin-angiotensin-aldosterone system, which is critically involved in extracellular fluid volume and blood pressure homeostasis of the body. R...

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
intracellular calcium activated chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
chloride transport IEA
Inferred from Electronic Annotation
more info
 
ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
chloride channel calcium activated 4-like
Names
calcium-activated chloride channel

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077356.2NP_001070824.1  chloride channel calcium activated 4-like precursor

    See identical proteins and their annotated locations for NP_001070824.1

    Status: PROVISIONAL

    Source sequence(s)
    AB256513
    UniProtKB/TrEMBL
    Q05KA7
    Related
    ENSRNOP00000052230.2, ENSRNOT00000055362.2
    Conserved Domains (3) summary
    cd00198
    Location:307464
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam08434
    Location:24889
    CLCA; Calcium-activated chloride channel
    cl19929
    Location:532572
    A2M_N; MG2 domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    250785534..250805445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    225815697..225835390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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