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Mef2c myocyte enhancer factor 2C [ Rattus norvegicus (Norway rat) ]

Gene ID: 499497, updated on 3-Jun-2018
Symbol
Mef2cprovided by RGD
Full Name
myocyte enhancer factor 2Cprovided by RGD
Primary source
RGD:1563119
See related
Ensembl:ENSRNOG00000033134 Vega:OTTRNOG00000000103
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563119
Expression
Biased expression in Muscle (RPKM 1118.3), Brain (RPKM 457.2) and 4 other tissues See more
Orthologs
See Mef2c in Genome Data Viewer
Location:
2q11
Exon count:
16
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (11658534..11822788)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (11521053..11684949)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691411 Neighboring gene uncharacterized LOC102552429 Neighboring gene uncharacterized LOC103691412 Neighboring gene microRNA 3597-2 Neighboring gene microRNA 9-2 Neighboring gene centrin 3

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adipogenesis, organism-specific biosystem (from WikiPathways)
    Adipogenesis, organism-specific biosystemThe different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compo...
  • Apelin signaling pathway, organism-specific biosystem (from KEGG)
    Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
  • CDO in myogenesis, organism-specific biosystem (from REACTOME)
    CDO in myogenesis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Delta-Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Delta-Notch Signaling Pathway, organism-specific biosystemThere are 4 Notch receptors in humans (Notch 1-4) that bind to a family of 5 ligands (Jagged 1 and 2 and Delta-like 1-3). The Notch receptors are expressed on the cell surface as heterodimeric protei...
  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Endochondral Ossification, organism-specific biosystem (from WikiPathways)
    Endochondral Ossification, organism-specific biosystem
    Endochondral Ossification
  • Fluid shear stress and atherosclerosis, organism-specific biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, organism-specific biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • Fluid shear stress and atherosclerosis, conserved biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, conserved biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • MAPK signaling pathway, organism-specific biosystem (from KEGG)
    MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
    MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • MAPK signaling pathway, conserved biosystem (from KEGG)
    MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • Myogenesis, organism-specific biosystem (from REACTOME)
    Myogenesis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Oxytocin signaling pathway, organism-specific biosystem (from KEGG)
    Oxytocin signaling pathway, organism-specific biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Oxytocin signaling pathway, conserved biosystem (from KEGG)
    Oxytocin signaling pathway, conserved biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Transcriptional misregulation in cancer, organism-specific biosystem (from KEGG)
    Transcriptional misregulation in cancer, organism-specific biosystem
    Transcriptional misregulation in cancer
  • Transcriptional misregulation in cancer, conserved biosystem (from KEGG)
    Transcriptional misregulation in cancer, conserved biosystem
    Transcriptional misregulation in cancer
  • cGMP-PKG signaling pathway, organism-specific biosystem (from KEGG)
    cGMP-PKG signaling pathway, organism-specific biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
  • cGMP-PKG signaling pathway, conserved biosystem (from KEGG)
    cGMP-PKG signaling pathway, conserved biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
AT DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
HMG box domain binding IEA
Inferred from Electronic Annotation
more info
 
HMG box domain binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II activating transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
RNA polymerase II transcription factor activity, sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
activating transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
core promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
core promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
B cell homeostasis IEA
Inferred from Electronic Annotation
more info
 
B cell homeostasis ISO
Inferred from Sequence Orthology
more info
 
B cell homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
B cell proliferation IEA
Inferred from Electronic Annotation
more info
 
B cell proliferation ISO
Inferred from Sequence Orthology
more info
 
B cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
B cell receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
B cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
MAPK cascade IEA
Inferred from Electronic Annotation
more info
 
MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
blood vessel development IEA
Inferred from Electronic Annotation
more info
 
blood vessel development ISO
Inferred from Sequence Orthology
more info
 
blood vessel remodeling IEA
Inferred from Electronic Annotation
more info
 
blood vessel remodeling ISO
Inferred from Sequence Orthology
more info
 
cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cardiac muscle hypertrophy in response to stress IEA
Inferred from Electronic Annotation
more info
 
cardiac muscle hypertrophy in response to stress ISO
Inferred from Sequence Orthology
more info
 
cardiac ventricle formation IEA
Inferred from Electronic Annotation
more info
 
cardiac ventricle formation ISO
Inferred from Sequence Orthology
more info
 
cartilage morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cartilage morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cell fate commitment ISO
Inferred from Sequence Orthology
more info
 
cell morphogenesis involved in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
cell morphogenesis involved in neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
cell morphogenesis involved in neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to calcium ion IEA
Inferred from Electronic Annotation
more info
 
cellular response to calcium ion ISO
Inferred from Sequence Orthology
more info
 
cellular response to calcium ion ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to drug IEA
Inferred from Electronic Annotation
more info
 
cellular response to drug ISO
Inferred from Sequence Orthology
more info
 
cellular response to drug ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to fluid shear stress IEA
Inferred from Electronic Annotation
more info
 
cellular response to fluid shear stress ISO
Inferred from Sequence Orthology
more info
 
cellular response to fluid shear stress ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to glucose stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to growth factor stimulus IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
cellular response to lipopolysaccharide ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to parathyroid hormone stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to parathyroid hormone stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to retinoic acid IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to transforming growth factor beta stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to transforming growth factor beta stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to trichostatin A IEA
Inferred from Electronic Annotation
more info
 
cellular response to trichostatin A ISO
Inferred from Sequence Orthology
more info
 
cellular response to trichostatin A ISS
Inferred from Sequence or Structural Similarity
more info
 
chondrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
chondrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
dentate gyrus development IEP
Inferred from Expression Pattern
more info
PubMed 
embryonic skeletal system morphogenesis ISO
Inferred from Sequence Orthology
more info
 
embryonic viscerocranium morphogenesis IEA
Inferred from Electronic Annotation
more info
 
embryonic viscerocranium morphogenesis ISO
Inferred from Sequence Orthology
more info
 
endochondral ossification IEA
Inferred from Electronic Annotation
more info
 
endochondral ossification ISO
Inferred from Sequence Orthology
more info
 
epithelial cell proliferation involved in renal tubule morphogenesis IEA
Inferred from Electronic Annotation
more info
 
epithelial cell proliferation involved in renal tubule morphogenesis ISO
Inferred from Sequence Orthology
more info
 
epithelial cell proliferation involved in renal tubule morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
excitatory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 
excitatory postsynaptic potential ISO
Inferred from Sequence Orthology
more info
 
excitatory postsynaptic potential ISS
Inferred from Sequence or Structural Similarity
more info
 
germinal center formation IEA
Inferred from Electronic Annotation
more info
 
germinal center formation ISO
Inferred from Sequence Orthology
more info
 
germinal center formation ISS
Inferred from Sequence or Structural Similarity
more info
 
glomerulus morphogenesis IEA
Inferred from Electronic Annotation
more info
 
glomerulus morphogenesis ISO
Inferred from Sequence Orthology
more info
 
glomerulus morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
heart development IEP
Inferred from Expression Pattern
more info
PubMed 
heart development ISO
Inferred from Sequence Orthology
more info
 
heart looping IEA
Inferred from Electronic Annotation
more info
 
heart looping ISO
Inferred from Sequence Orthology
more info
 
heart looping ISS
Inferred from Sequence or Structural Similarity
more info
 
humoral immune response IEA
Inferred from Electronic Annotation
more info
 
humoral immune response ISO
Inferred from Sequence Orthology
more info
 
humoral immune response ISS
Inferred from Sequence or Structural Similarity
more info
 
learning or memory IEA
Inferred from Electronic Annotation
more info
 
learning or memory ISO
Inferred from Sequence Orthology
more info
 
learning or memory ISS
Inferred from Sequence or Structural Similarity
more info
 
melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
melanocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
melanocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
monocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
monocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
muscle cell fate determination IEA
Inferred from Electronic Annotation
more info
 
muscle cell fate determination ISO
Inferred from Sequence Orthology
more info
 
myotube differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of ossification ISO
Inferred from Sequence Orthology
more info
 
negative regulation of ossification ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of vascular associated smooth muscle cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of vascular endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of vascular smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
nephron tubule epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
nephron tubule epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
nephron tubule epithelial cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
neural crest cell differentiation IEA
Inferred from Electronic Annotation
more info
 
neural crest cell differentiation ISO
Inferred from Sequence Orthology
more info
 
neural crest cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron development ISO
Inferred from Sequence Orthology
more info
 
neuron development ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron migration IEA
Inferred from Electronic Annotation
more info
 
neuron migration ISO
Inferred from Sequence Orthology
more info
 
neuron migration ISS
Inferred from Sequence or Structural Similarity
more info
 
osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
 
osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
outflow tract morphogenesis IEA
Inferred from Electronic Annotation
more info
 
outflow tract morphogenesis ISO
Inferred from Sequence Orthology
more info
 
platelet formation IEA
Inferred from Electronic Annotation
more info
 
platelet formation ISO
Inferred from Sequence Orthology
more info
 
platelet formation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of B cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of B cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of B cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of alkaline phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of alkaline phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of alkaline phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of behavioral fear response IEA
Inferred from Electronic Annotation
more info
 
positive regulation of behavioral fear response ISO
Inferred from Sequence Orthology
more info
 
positive regulation of behavioral fear response ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of bone mineralization IEA
Inferred from Electronic Annotation
more info
 
positive regulation of bone mineralization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of bone mineralization ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cardiac muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cardiac muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cardiac muscle cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cardiac muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cardiac muscle cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cardiac muscle hypertrophy IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation in bone marrow IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation in bone marrow ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of macrophage apoptotic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of macrophage apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of macrophage apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of myoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of myoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of skeletal muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of skeletal muscle tissue development ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
primary heart field specification IEA
Inferred from Electronic Annotation
more info
 
primary heart field specification ISO
Inferred from Sequence Orthology
more info
 
primary heart field specification ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of AMPA receptor activity IEA
Inferred from Electronic Annotation
more info
 
regulation of AMPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
regulation of AMPA receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of NMDA receptor activity IEA
Inferred from Electronic Annotation
more info
 
regulation of NMDA receptor activity ISO
Inferred from Sequence Orthology
more info
 
regulation of NMDA receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 
regulation of dendritic spine development ISO
Inferred from Sequence Orthology
more info
 
regulation of dendritic spine development ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of germinal center formation IEA
Inferred from Electronic Annotation
more info
 
regulation of germinal center formation ISO
Inferred from Sequence Orthology
more info
 
regulation of germinal center formation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of megakaryocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
regulation of megakaryocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of megakaryocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
regulation of neuron apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 
regulation of neurotransmitter secretion ISO
Inferred from Sequence Orthology
more info
 
regulation of neurotransmitter secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of sarcomere organization IEA
Inferred from Electronic Annotation
more info
 
regulation of sarcomere organization ISO
Inferred from Sequence Orthology
more info
 
regulation of synapse assembly IEA
Inferred from Electronic Annotation
more info
 
regulation of synapse assembly ISO
Inferred from Sequence Orthology
more info
 
regulation of synaptic activity IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic activity ISO
Inferred from Sequence Orthology
more info
 
regulation of synaptic activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic plasticity IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic plasticity ISO
Inferred from Sequence Orthology
more info
 
regulation of synaptic plasticity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic transmission, glutamatergic ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
renal tubule morphogenesis ISO
Inferred from Sequence Orthology
more info
 
renal tubule morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
response to nutrient levels IEP
Inferred from Expression Pattern
more info
PubMed 
response to vitamin E IEP
Inferred from Expression Pattern
more info
PubMed 
roof of mouth development IEA
Inferred from Electronic Annotation
more info
 
roof of mouth development ISO
Inferred from Sequence Orthology
more info
 
secondary heart field specification IEA
Inferred from Electronic Annotation
more info
 
secondary heart field specification ISO
Inferred from Sequence Orthology
more info
 
secondary heart field specification ISS
Inferred from Sequence or Structural Similarity
more info
 
sinoatrial valve morphogenesis IEA
Inferred from Electronic Annotation
more info
 
sinoatrial valve morphogenesis ISO
Inferred from Sequence Orthology
more info
 
sinoatrial valve morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
smooth muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
smooth muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transdifferentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
ventricular cardiac muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
ventricular cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
ventricular cardiac muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nuclear chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
postsynapse IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISS
Inferred from Sequence or Structural Similarity
more info
 
sarcomere IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
myocyte-specific enhancer factor 2C

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    11658534..11822788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591165.1XP_017446654.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/TrEMBL
    A0A096MK43
    Related
    ENSRNOP00000068373.1, OTTRNOP00000000041, ENSRNOT00000076239.1, OTTRNOT00000000110
  2. XM_017591163.1XP_017446652.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Related
    ENSRNOP00000068307.1, OTTRNOP00000000057, ENSRNOT00000076710.2, OTTRNOT00000000131
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  3. XM_017591167.1XP_017446656.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/TrEMBL
    A0A096MJ09
    Related
    ENSRNOP00000067948.1, OTTRNOP00000000058, ENSRNOT00000076992.2, OTTRNOT00000000132
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  4. XM_017591168.1XP_017446657.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A096MK01
    Related
    ENSRNOP00000068328.1, OTTRNOP00000000061, ENSRNOT00000076408.2, OTTRNOT00000000135
  5. XM_017591164.1XP_017446653.1  myocyte-specific enhancer factor 2C isoform X2

    UniProtKB/TrEMBL
    A0A096MK88
    Related
    ENSRNOP00000068421.1, OTTRNOP00000000042, ENSRNOT00000076084.2, OTTRNOT00000000111
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  6. XM_017591166.1XP_017446655.1  myocyte-specific enhancer factor 2C isoform X4

    UniProtKB/TrEMBL
    A0A096MKI4
    Related
    ENSRNOP00000068527.1, OTTRNOP00000000064, ENSRNOT00000076230.2, OTTRNOT00000000138
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. XM_006231731.2XP_006231793.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006231793.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  8. XM_008760642.2XP_008758864.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_008758864.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  9. XM_006231733.3XP_006231795.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006231795.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    10288159..10449731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594372.1XP_017449861.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/TrEMBL
    A0A096MK43
  2. XM_017594354.1XP_017449843.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  3. XM_017594376.1XP_017449865.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/TrEMBL
    A0A096MJ09
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  4. XM_017594379.1XP_017449868.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A096MK01
  5. XM_017594367.1XP_017449856.1  myocyte-specific enhancer factor 2C isoform X2

    UniProtKB/TrEMBL
    A0A096MK88
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  6. XM_017594374.1XP_017449863.1  myocyte-specific enhancer factor 2C isoform X4

    UniProtKB/TrEMBL
    A0A096MKI4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. XM_006223955.3XP_006224017.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006224017.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  8. XM_008775027.2XP_008773249.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_008773249.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  9. XM_006223957.3XP_006224019.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006224019.1

    UniProtKB/Swiss-Prot
    A0A096MJY4
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
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