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OR2C1 olfactory receptor family 2 subfamily C member 1 [ Homo sapiens (human) ]

Gene ID: 4993, updated on 23-Nov-2021


Official Symbol
OR2C1provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily C member 1provided by HGNC
Primary source
See related
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OLFmf3; OR2C2P
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

See OR2C1 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (3355889..3357306)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3405889..3407306)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 75a Neighboring gene ribosomal protein L7 like 1 pseudogene Neighboring gene uncharacterized LOC105371059 Neighboring gene MT-CO2 pseudogene 28 Neighboring gene MT-CO1 pseudogene 28

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information



Clone Names

  • MGC95444, MGC163200

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
enables odorant binding IEA
Inferred from Electronic Annotation
more info
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
located_in plasma membrane TAS
Traceable Author Statement
more info

General protein information

Preferred Names
olfactory receptor 2C1
olfactory receptor 2C2
olfactory receptor OR16-1
olfactory receptor OR16-2
olfactory receptor, family 2, subfamily C, member 2 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012368.3NP_036500.2  olfactory receptor 2C1

    See identical proteins and their annotated locations for NP_036500.2

    Status: VALIDATED

    Source sequence(s)
    AC025283, BC069158, BC126269
    Consensus CDS
    ENSP00000307726.2, ENST00000304936.4
    Conserved Domains (1) summary
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)
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