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Acer3 alkaline ceramidase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499210, updated on 19-Apr-2019

Summary

Official Symbol
Acer3provided by RGD
Official Full Name
alkaline ceramidase 3provided by RGD
Primary source
RGD:1561254
See related
Ensembl:ENSRNOG00000036866
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Phca; RGD1561254
Expression
Biased expression in Spleen (RPKM 172.5), Lung (RPKM 139.0) and 9 other tissues See more
Orthologs

Genomic context

See Acer3 in Genome Data Viewer
Location:
1q32
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (163160987..163263621, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (169367775..169469576, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene calpain 5 Neighboring gene olfactory marker protein Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 Neighboring gene uncharacterized LOC108349448 Neighboring gene tsukushi, small leucine rich proteoglycan

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
N-acylsphingosine amidohydrolase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium ion binding ISO
Inferred from Sequence Orthology
more info
PubMed 
dihydroceramidase activity IEA
Inferred from Electronic Annotation
more info
 
dihydroceramidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
phytoceramidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phytoceramidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
ceramide catabolic process IEA
Inferred from Electronic Annotation
more info
 
ceramide catabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
inflammatory response ISO
Inferred from Sequence Orthology
more info
PubMed 
myelination IEA
Inferred from Electronic Annotation
more info
 
myelination ISO
Inferred from Sequence Orthology
more info
PubMed 
phytosphingosine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phytosphingosine biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of programmed cell death IEA
Inferred from Electronic Annotation
more info
 
regulation of programmed cell death ISO
Inferred from Sequence Orthology
more info
PubMed 
sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
sphingosine biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of Golgi membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
integral component of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
alkaline ceramidase 3
Names
phytoceramidase, alkaline
XP_001065019.2
XP_008758031.1
XP_017443612.1
XP_017445677.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    163160987..163263621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008759809.2XP_008758031.1  alkaline ceramidase 3 isoform X1

    See identical proteins and their annotated locations for XP_008758031.1

    UniProtKB/TrEMBL
    F1M6P3
    Related
    ENSRNOP00000019987.5, ENSRNOT00000019987.7
    Conserved Domains (1) summary
    pfam05875
    Location:9259
    Ceramidase; Ceramidase
  2. XM_017590188.1XP_017445677.1  alkaline ceramidase 3 isoform X2

    Conserved Domains (1) summary
    pfam05875
    Location:1161
    Ceramidase; Ceramidase

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    150595013..150696477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001065019.6XP_001065019.2  alkaline ceramidase 3 isoform X1

    See identical proteins and their annotated locations for XP_001065019.2

    UniProtKB/TrEMBL
    F1M6P3
    Conserved Domains (1) summary
    pfam05875
    Location:9259
    Ceramidase; Ceramidase
  2. XM_017588123.1XP_017443612.1  alkaline ceramidase 3 isoform X2

    Conserved Domains (1) summary
    pfam05875
    Location:1161
    Ceramidase; Ceramidase
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