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OR1F1 olfactory receptor family 1 subfamily F member 1 [ Homo sapiens (human) ]

Gene ID: 4992, updated on 13-May-2022

Summary

Official Symbol
OR1F1provided by HGNC
Official Full Name
olfactory receptor family 1 subfamily F member 1provided by HGNC
Primary source
HGNC:HGNC:8194
See related
Ensembl:ENSG00000168124 MIM:603232; AllianceGenome:HGNC:8194
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OLFMF; OR1F4; OR1F5; OR1F6; OR1F7; OR1F8; OR1F9; OR1F10; OR16-36; OR16-37; OR16-88; OR16-89; OR16-90; OR1F13P; OR3-145; ORL1023
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OR1F1 in Genome Data Viewer
Location:
16p13.3
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (3188204..3206506)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (3214814..3233497)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3238204..3256506)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene tRNA-Pro (anticodon TGG) 3-4 Neighboring gene tRNA-Pro (anticodon TGG) 3-5 Neighboring gene tRNA-Pro (anticodon AGG) 2-8 Neighboring gene tRNA-Lys (anticodon CTT) 4-1 Neighboring gene tRNA-Pro (anticodon AGG) 1-1 Neighboring gene tRNA-Lys (anticodon CTT) 14-1 Neighboring gene olfactory receptor family 1 subfamily F member 2 pseudogene Neighboring gene zinc finger protein 200

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • AJ003147.9

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 1F1
Names
olfactory receptor, family 1, subfamily F, member 10
olfactory receptor, family 1, subfamily F, member 13 pseudogene
olfactory receptor, family 1, subfamily F, member 4
olfactory receptor, family 1, subfamily F, member 5
olfactory receptor, family 1, subfamily F, member 6
olfactory receptor, family 1, subfamily F, member 7
olfactory receptor, family 1, subfamily F, member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370639.1NP_001357568.1  olfactory receptor 1F1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AJ003147
    Conserved Domains (1) summary
    cd15918
    Location:35304
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001370640.3NP_001357569.1  olfactory receptor 1F1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AJ003147
    Conserved Domains (1) summary
    cd15918
    Location:35304
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_001370641.1NP_001357570.1  olfactory receptor 1F1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AJ003147
    Conserved Domains (1) summary
    cd15918
    Location:25294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  4. NM_012360.2NP_036492.1  olfactory receptor 1F1 isoform 2

    See identical proteins and their annotated locations for NP_036492.1

    Status: VALIDATED

    Source sequence(s)
    AJ003147
    Consensus CDS
    CCDS10496.1
    UniProtKB/Swiss-Prot
    O43749
    Related
    ENSP00000305424.2, ENST00000304646.2
    Conserved Domains (1) summary
    cd15918
    Location:25294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    3188204..3206506
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522507.4XP_011520809.1  olfactory receptor 1F1 isoform X1

    See identical proteins and their annotated locations for XP_011520809.1

    UniProtKB/Swiss-Prot
    O43749
    Conserved Domains (1) summary
    cd15918
    Location:25294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    3214814..3233497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)