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Fam114a1 family with sequence similarity 114, member A1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498366, updated on 3-Jun-2026
Official Symbol
Fam114a1provided by RGD
Official Full Name
family with sequence similarity 114, member A1provided by RGD
Primary source
RGD:1560201
See related
Ensembl:ENSRNOG00000026504 AllianceGenome:RGD:1560201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560201
Summary
Predicted to act upstream of or within several processes, including angiotensin-activated signaling pathway; fibroblast activation; and fibroblast migration. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Orthologous to human FAM114A1 (family with sequence similarity 114 member A1). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Heart (RPKM 88.3), Lung (RPKM 83.5) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Fam114a1 in Genome Data Viewer
Location:
14p11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (43629349..43699800, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (43275693..43346154, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (44941705..45012299, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene kelch-like family member 5 Neighboring gene uncharacterized LOC102556650 Neighboring gene transmembrane protein 156 Neighboring gene toll-like receptor 6 Neighboring gene toll-like receptor 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. Bhatnagar S, et al. J Biol Chem, 2014 Sep 5. PMID 25002582, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within angiotensin-activated signaling pathway ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within connective tissue replacement ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within fibroblast activation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within fibroblast migration ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within fibroblast proliferation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within gene expression ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within heart valve morphogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within inflammatory response ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within tissue remodeling ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
protein NOXP20

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399036.1 → NP_001385965.1  protein NOXP20

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A8I5ZXD6, D4A777
    Related
    ENSRNOP00000002883.6, ENSRNOT00000002883.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    43629349..43699800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039092750.2 → XP_038948678.1  protein NOXP20 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZXD6, D4A777
    Conserved Domains (1) summary
    pfam05334
    Location:123 → 298
    DUF719; Protein of unknown function (DUF719)

  2. XM_039092749.2 → XP_038948677.1  protein NOXP20 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZXD6, D4A777
    Conserved Domains (1) summary
    pfam05334
    Location:123 → 298
    DUF719; Protein of unknown function (DUF719)

  3. XM_039092751.2 → XP_038948679.1  protein NOXP20 isoform X2

    Conserved Domains (1) summary
    pfam05334
    Location:19 → 173
    DUF719; Protein of unknown function (DUF719)
Nucleotide Protein Strain
Heading Accession and Version

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